SNORD114-4: A Potential Drug Target and Biomarker (G767580)

Target Name: SNORD114-4

NCBI ID: G767580

SNORD114-4

Other Name(s): Small nucleolar RNA, C/D box 114-4 | 14q(II-4) | small nucleolar RNA, C/D box 114-4

SNORD114-4: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA) is a class of non-coding RNAs that play critical roles in various cellular processes, including DNA replication, gene expression, and RNA processing. One of the most well-studied snRNAs is SNORD114-4, which is located in the C/D box region on chromosome 17.

The C/D box region is a common site for snRNA structures, and various studies have identified conserved elements that are involved in their formation. SNORD114-4 is a 24-nt RNA molecule that contains a unique core structure composed of a hairpin loop and a 2'-overhang. The loop region contains a series of conserved basic amino acids that are involved in the formation of the hairpin loop, while the 2'-overhang contains a conserved GCA sequence that is involved in the formation of the loop.

Functional studies have shown that SNORD114-4 is involved in various cellular processes, including cell growth, apoptosis, and DNA replication. For example, studies have shown that SNORD114-4 is involved in the regulation of cell growth and has been shown to play a role in the development of cancer. Additionally, SNORD114-4 has been shown to be involved in the regulation of apoptosis, which is the process by which cells undergo programmed cell death. This is important for understanding the mechanisms of cell death and for the development of therapeutic strategies for diseases such as cancer.

Another potential function of SNORD114-4 is as a biomarker for various diseases. For example, studies have shown that SNORD114-4 is downregulated in various diseases, including cancer, neurodegenerative diseases, and mental disorders. This suggests that SNORD114-4 may be a useful biomarker for these diseases and that targeting it may be a potential therapeutic strategy.

In addition to its potential as a drug target, SNORD114-4 also has potential as a biomarker for certain diseases. For example, studies have shown that SNORD114-4 is downregulated in various diseases, including cancer, neurodegenerative diseases, and mental disorders. This suggests that SNORD114-4 may be a useful biomarker for these diseases and that targeting it may be a potential therapeutic strategy.

In conclusion, SNORD114-4 is a well-studied snRNA that is involved in various cellular processes and has been shown to play a role in the regulation of cell growth, apoptosis, and DNA replication. In addition to its potential as a drug target, SNORD114-4 also has potential as a biomarker for various diseases. Further research is needed to fully understand its functions and to develop therapeutic strategies for diseases where it is downregulated.

Protein Name: Small Nucleolar RNA, C/D Box 114-4

The "SNORD114-4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORD114-4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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