Target Name: ZP2
NCBI ID: G7783
Review Report on ZP2 Target / Biomarker Content of Review Report on ZP2 Target / Biomarker
ZP2
Other Name(s): ZP2 variant 1 | Zp-2 | Zona pellucida sperm-binding protein 2 | ZPA | Zona pellucida glycoprotein 2, transcript variant 1 | Zona pellucida protein A | ZP2_HUMAN | zona pellucida 2 | Zona pellucida glycoprotein ZP2 | zona pellucida protein A | zona pellucida glycoprotein ZP2 | zona pellucida glycoprotein 2 | zona pellucida glycoprotein 2 (sperm receptor) | Processed zona pellucida sperm-binding protein 2 | Zona pellucida glycoprotein 2 | Zona pellucida sperm-binding protein 2 (isoform 1) | OOMD6

ZP2: A Potential Drug Target Or Biomarker for Various Diseases

ZP2, or ZP2 variant 1, is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the Zonus proboscide family, which are a group of transmembrane proteins that are involved in various cellular processes, including cell signaling and tissue organization.

Recent studies have identified ZP2 as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and gastrointestinal diseases. ZP2 has been shown to play a role in several cellular processes that are important for disease development and progression, including the regulation of cell signaling pathways, cell adhesion, and angiogenesis.

One of the key functions of ZP2 is its role in cell signaling. ZP2 has been shown to be involved in several signaling pathways that are important for brain development, function, and disease, including the Wnt signaling pathway, which is involved in the development and maintenance of the nervous system.

In addition to its role in cell signaling, ZP2 has also been shown to be involved in the regulation of cell adhesion. ZP2 has been shown to be involved in the formation of tight junctions, which are a type of cell-cell adhesion that is important for maintaining tissue structure and function.

Another function of ZP2 is its role in the regulation of angiogenesis, which is the process by which new blood vessels are formed. ZP2 has been shown to be involved in the regulation of angiogenesis, including the sprouting angiogenesis that occurs in the developing nervous system.

In addition to its role in cell signaling and angiogenesis, ZP2 has also been shown to be involved in the regulation of inflammation. ZP2 has been shown to be involved in the regulation of immune cell function, including the regulation of T cell development and the regulation of inflammation.

Given its involvement in several cellular processes that are important for disease development and progression, ZP2 has been identified as a potential drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and gastrointestinal diseases.

One of the main advantages of ZP2 as a drug target is its relatively simple structure, as it is a single transmembrane protein. This makes it easier to develop potential drugs that target ZP2, as well as to understand how the drug will interact with the protein.

In addition, ZP2 has been shown to be involved in several disease processes that are common, including cancer, neurodegenerative diseases, and gastrointestinal diseases. This makes it a promising target for the development of new treatments for these diseases.

Overall, ZP2 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to understand its role in disease and to develop effective treatments.

Protein Name: Zona Pellucida Glycoprotein 2

Functions: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy (PubMed:29895852). The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor (PubMed:29895852)

The "ZP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ZP3 | ZP4 | ZPBP | ZPBP2 | ZPLD1 | ZPLD2P | ZPR1 | ZRANB1 | ZRANB2 | ZRANB2-AS1 | ZRANB2-DT | ZRANB3 | ZRS | ZRSR2 | ZRSR2P1 | ZSCAN1 | ZSCAN10 | ZSCAN12 | ZSCAN12P1 | ZSCAN16 | ZSCAN16-AS1 | ZSCAN18 | ZSCAN2 | ZSCAN20 | ZSCAN21 | ZSCAN22 | ZSCAN23 | ZSCAN25 | ZSCAN26 | ZSCAN29 | ZSCAN30 | ZSCAN31 | ZSCAN32 | ZSCAN4 | ZSCAN5A | ZSCAN5B | ZSCAN5DP | ZSCAN9 | ZSWIM1 | ZSWIM2 | ZSWIM3 | ZSWIM4 | ZSWIM5 | ZSWIM5P2 | ZSWIM6 | ZSWIM7 | ZSWIM8 | ZSWIM9 | ZUP1 | ZW10 | ZWILCH | ZWINT | ZXDA | ZXDB | ZXDC | ZYG11A | ZYG11B | ZYX | ZZEF1 | ZZZ3