Target Name: RHO
NCBI ID: G6010
Review Report on RHO Target / Biomarker Content of Review Report on RHO Target / Biomarker
RHO
Other Name(s): OPSD_HUMAN | opsin 2, rod pigment | RP4 | opsin-2 | Opsin-2 | Rhodopsin | CSNBAD1 | Rod pigment | OPN2 | rhodopsin

Rho (OPSD_HUMAN): A Protein Involved in Fetal Development and Disease

Rho (OPSD_HUMAN) is a protein that is expressed in various tissues of the human body, including the placenta, bone marrow, and peripheral blood. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a crucial role in cellular signaling.

Overview of Rho (OPSD_HUMAN)

Rho (OPSD_HUMAN) is a 21-kDa protein that is expressed in various tissues of the human body. It is mainly expressed in the placenta, which is a vital organ that plays a critical role in the development and maintenance of fetal tissues. Rho ( OPSD_HUMAN) is also expressed in the bone marrow and peripheral blood.

The Rho (OPSD_HUMAN) protein is a member of the GPCR family, which is a large superfamily of transmembrane proteins that play a crucial role in cellular signaling. GPCR family proteins are involved in a wide range of physiological processes in the body, including sensory perception , neurotransmission, and hormone signaling.

Expression of Rho (OPSD_HUMAN)

Rho (OPSD_HUMAN) is expressed in various tissues of the human body, including the placenta, bone marrow, and peripheral blood. The levels of Rho (OPSD_HUMAN) expression vary depending on the specific cell type and the physiological context. For example, Rho ( OPSD_HUMAN) is highly expressed in the placenta, which is responsible for providing oxygen and nutrients to the developing fetal tissues.

Rho (OPSD_HUMAN) has been shown to play a critical role in fetal development and growth. It is involved in the regulation of cellular processes that are essential for normal fetal development, such as cell proliferation, migration, and angiogenesis.

Drug Targeting Rho (OPSD_HUMAN)

Rho (OPSD_HUMAN) is a drug target of great interest because of its involvement in various physiological processes in the body. Several studies have suggested that inhibiting Rho (OPSD_HUMAN) activity may be a useful strategy for treating various diseases.

One of the potential therapeutic targets for Rho (OPSD_HUMAN) is the use of small molecules that can inhibit the activity of Rho (OPSD_HUMAN). These small molecules can be administered to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Another approach to targeting Rho (OPSD_HUMAN) is the use of monoclonal antibodies (mAbs). These antibodies can be used to specifically target Rho (OPSD_HUMAN) and can be used to treat various diseases.

Biomarker Analysis

Rho (OPSD_HUMAN) has also been used as a biomarker for various diseases. The levels of Rho (OPSD_HUMAN) expression can be used as a marker for cancer, neurodegenerative diseases, and autoimmune diseases.

For example, studies have shown that Rho (OPSD_HUMAN) is highly expressed in various tissues of people with cancer. Therefore, the levels of Rho (OPSD_HUMAN) expression can be used as a biomarker for cancer.

Conclusion

Rho (OPSD_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the GPCR family and plays a crucial role in cellular signaling. Rho (OPSD_HUMAN) is involved in the regulation of cellular processes that are essential for normal fetal development and growth.

The levels of Rho (OPSD_HUMAN) expression vary depending on the specific cell type and the physiological context. It is a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Furthermore, Rho (OPSD_HUMAN) has also been used as a biomarker for various diseases, including cancer. The levels of Rho (OPSD_HUMAN) expression can be used as a biomarker for cancer and can be used for the diagnosis and monitoring of cancer.

Overall, Rho (OPSD_HUMAN) is a protein that has significant roles in various physiological processes in the human body. Further research is needed to fully understand its functions and to develop effective strategies for targeting and treating it in various diseases.

Protein Name: Rhodopsin

Functions: Photoreceptor required for image-forming vision at low light intensity (PubMed:8107847, PubMed:7846071). Required for photoreceptor cell viability after birth (PubMed:2215617, PubMed:12566452). Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed:8107847, PubMed:28524165, PubMed:26200343, PubMed:28753425). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:28524165, PubMed:26200343)

The "RHO Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RHO comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Rho GTPase | Rho kinase (ROCK) | RHOA | RHOB | RHOBTB1 | RHOBTB2 | RHOBTB3 | RHOC | RHOD | RHOF | RHOG | RHOH | RHOJ | RHOQ | RHOQP3 | RHOT1 | RHOT2 | RHOU | RHOV | RHOXF1 | RHOXF1-AS1 | RHOXF1P1 | RHOXF2 | RHOXF2B | RHPN1 | RHPN1-AS1 | RHPN2 | RIBC1 | RIBC2 | Ribonuclease | Ribonuclease H | Ribonuclease MRP | Ribonuclease P Complex | Ribosomal protein S6 kinase (RSK) | Ribosomal Protein S6 Kinase, 70kDa (p70S6K) | Ribosomal Protein S6 Kinase, 90kDa | Ribosomal subunit 40S | Ribosome-associated complex | RIC1 | RIC3 | RIC8A | RIC8B | RICH1-AMOT complex | RICTOR | RIDA | RIF1 | RIGI | RIIAD1 | RILP | RILPL1 | RILPL2 | RIMBP2 | RIMBP3 | RIMBP3B | RIMBP3C | RIMKLA | RIMKLB | RIMKLBP2 | RIMOC1 | RIMS1 | RIMS2 | RIMS3 | RIMS4 | RIN1 | RIN2 | RIN3 | RING1 | RINL | RINT1 | RIOK1 | RIOK2 | RIOK3 | RIOK3P1 | RIOX1 | RIOX2 | RIPK1 | RIPK2 | RIPK3 | RIPK4 | RIPOR1 | RIPOR2 | RIPOR3 | RIPPLY1 | RIPPLY2 | RIPPLY3 | RIT1 | RIT2 | RITA1 | RLBP1 | RLF | RLIM | RLIMP1 | RLN1 | RLN2 | RLN3 | RMC1 | RMDN1 | RMDN2 | RMDN3 | RMI1