Target Name: RHBG
NCBI ID: G57127
Review Report on RHBG Target / Biomarker Content of Review Report on RHBG Target / Biomarker
RHBG
Other Name(s): Rhesus blood group, B glycoprotein | Rh type B glycoprotein | Rhesus blood group family type B glycoprotein | Ammonium transporter Rh type B (isoform a) | RHBG_HUMAN | SLC42A2 | Rh family B glycoprotein, transcript variant 3 | Rh family B glycoprotein, transcript variant 1 | Ammonium transporter Rh type B | RHBG variant 1 | Rh family B glycoprotein | Rh family type B glycoprotein | Ammonium transporter Rh type B (isoform c) | RHBG variant 3

Understanding RHBG: Potential Drug Target and Biomarker

RHBG, or Rhesus Blood Group B, is a protein that is found on the surface of red blood cells in humans. It is a type of glycoprotein, which means it consists of a protein and a sugar molecule called glucose. There are four different types of RHBG, each with a different sugar molecule on it. These types are RHBG A, RHBG B, RHBG AB, and RHBG O.

RHBG is an important protein that helps keep the blood cells healthy and functional. It is part of the blood surface antigen (BSA) complex, which is a group of proteins that help regulate the immune response and keep the blood cells from being rejected by the body. RHBG plays a key role in this system by helping to recognize and resist foreign substances that could cause an immune response.

One of the reasons RHBG is a potential drug target is because it is involved in many different processes in the body. For example, it is involved in the development and maintenance of the immune system, as well as the regulation of inflammation. It is also involved in the development and maintenance of the blood cells themselves, as well as the regulation of the blood clotting system.

In addition to its role in the immune system, RHBG is also a potential biomarker for some diseases. For example, people with genetic disorders that affect the immune system, such as sickle cell anemia or thalassemia, may have abnormal levels of RHBG in their blood. This could be used as a diagnostic tool to help doctors diagnose these disorders.

Another potential use for RHBG is as a therapy for some diseases. For example, some researchers are exploring the use of RHBG as a potential treatment for cancer, by using it to deliver small amounts of the drug to cancer cells in order to inhibit their growth.

Overall, RHBG is a complex and important protein that plays a key role in many different processes in the body. As a potential drug target and biomarker, it has the potential to revolutionize our understanding of these important proteins and their functions.

Protein Name: Rh Family B Glycoprotein

Functions: Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (PubMed:15284342, PubMed:15929723, PubMed:24077989). May act as a CO2 channel providing for renal acid secretion (PubMed:24077989)

The "RHBG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RHBG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RHCE | RHCG | RHD | RHEB | RHEBL1 | RHEBP1 | RHEX | RHNO1 | RHO | Rho GTPase | Rho kinase (ROCK) | RHOA | RHOB | RHOBTB1 | RHOBTB2 | RHOBTB3 | RHOC | RHOD | RHOF | RHOG | RHOH | RHOJ | RHOQ | RHOQP3 | RHOT1 | RHOT2 | RHOU | RHOV | RHOXF1 | RHOXF1-AS1 | RHOXF1P1 | RHOXF2 | RHOXF2B | RHPN1 | RHPN1-AS1 | RHPN2 | RIBC1 | RIBC2 | Ribonuclease | Ribonuclease H | Ribonuclease MRP | Ribonuclease P Complex | Ribosomal protein S6 kinase (RSK) | Ribosomal Protein S6 Kinase, 70kDa (p70S6K) | Ribosomal Protein S6 Kinase, 90kDa | Ribosomal subunit 40S | Ribosome-associated complex | RIC1 | RIC3 | RIC8A | RIC8B | RICH1-AMOT complex | RICTOR | RIDA | RIF1 | RIGI | RIIAD1 | RILP | RILPL1 | RILPL2 | RIMBP2 | RIMBP3 | RIMBP3B | RIMBP3C | RIMKLA | RIMKLB | RIMKLBP2 | RIMOC1 | RIMS1 | RIMS2 | RIMS3 | RIMS4 | RIN1 | RIN2 | RIN3 | RING1 | RINL | RINT1 | RIOK1 | RIOK2 | RIOK3 | RIOK3P1 | RIOX1 | RIOX2 | RIPK1 | RIPK2 | RIPK3 | RIPK4 | RIPOR1 | RIPOR2 | RIPOR3 | RIPPLY1 | RIPPLY2 | RIPPLY3 | RIT1 | RIT2 | RITA1 | RLBP1 | RLF | RLIM