Study on C1orf198: Potential Drug Target Or Biomarker for Various Diseases

Target Name: C1orf198

NCBI ID: G84886

C1orf198

Study on C1orf198: Potential Drug Target Or Biomarker for Various Diseases

C1orf198, also known as chromosome 1 open reading frame 198, is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique genetic mutation has led to a wide range of biological phenomena that have been studied extensively in both humans and animals.

The C1orf198 gene is located on chromosome 1, which is one of the most highly conserved regions of the human genome. It encodes a protein that is essential for the development and maintenance of tissues, including muscle, nerve, and heart cells. The protein is Involved in a variety of cellular processes, including cell signaling, DNA replication, and stress response.

The C1orf198 gene has been mutated various times, leading to a gain or loss of various amino acid residues. The most common mutation is a missense mutation, which results in the substitution of a glutamic acid for a lysine residue at position 612. This mutation has has been shown to cause a range of neurodegenerative symptoms, including progressive muscle weakness, muscle rigidity, and difficulty with speech and balance.

Other mutations that have been identified in the C1orf198 gene include a double mutation, which results in the substitution of a thymine residue for a guanine residue at position 769, and a substitution mutation, which results in the substitution of a aspartic acid for a glutamic acid at position 1064. These mutations have not been shown to cause any significant neurodegenerative symptoms.

In addition to its effects on neurodegenerative diseases, C1orf198 has also been studied for its potential as a drug target or biomarker for cancer. The C198 protein is known to play a role in cell signaling and has been shown to be involved in the development and progression of various cancers, including breast, ovarian, and colorectal cancers.

One of the most promising aspects of C198 as a drug target is its ability to interact with various signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in a wide range of cellular processes, including cell survival, angiogenesis, and inflammation . By targeting this pathway, researchers hope to develop drugs that can inhibit the growth and survival of cancer cells.

Another promising aspect of C198 is its ability to be targeted by small molecules. C198 has been shown to be highly sensitive to small changes in the cellular environment, including changes in pH and ionic balance. This makes it a promising target for drugs that can alter these factors, such as those that target ion channels or enzymes involved in pH regulation.

In addition to its potential as a drug target or biomarker, C198 has also been studied for its potential role in other biological processes, including cell signaling, DNA replication, and stress response. These studies have led to a greater understanding of the genetic and molecular underpinnings of C198's various functions.

Overall, C1rf198 is a gene that has a wide range of potential applications as a drug target or biomarker for various diseases. Its unique genetic mutation has led to a range of biological phenomena that have been studied extensively, and its potential as a drug target or biomarker is a promising area of 鈥嬧?媟esearch. Further studies are needed to fully understand the genetic and molecular underpinnings of C198 and its potential as a drug.

Protein Name: Chromosome 1 Open Reading Frame 198

The "C1orf198 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C1orf198 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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