Target Name: TNK1
NCBI ID: G8711
Review Report on TNK1 Target / Biomarker Content of Review Report on TNK1 Target / Biomarker
TNK1
Other Name(s): KOS1 | Non-receptor tyrosine-protein kinase TNK1 | CD38 negative kinase 1 | tyrosine kinase non receptor 1 | TNK1 variant 2 | MGC46193 | Tyrosine kinase non receptor 1, transcript variant 2 | TNK1_HUMAN | Non-receptor tyrosine-protein kinase TNK1 (isoform 2)

TNK1: A Multi-Functional Protein Target for Drug Development

TNK1 (KOS1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and intestines. It is a member of the TKLF1 family, which is known for its role in regulating gene expression and cell signaling.

One of the things that makes TNK1 an interesting drug target is its role in the regulation of pain. TNK1 has been shown to play a key role in the development and progression of pain, particularly in inflammatory pain.

In addition, TNK1 has also been shown to be involved in the regulation of inflammation and immune responses. This makes it an attractive target for drugs that are designed to treat inflammatory diseases, such as rheumatoid arthritis and colitis.

Another potential application of TNK1 as a drug target is its role in the regulation of cell growth and division. TNK1 has been shown to play a negative role in the regulation of cell proliferation, which makes it an attractive target for drugs that are designed to inhibit cancer growth.

In addition to its potential as a drug target, TNK1 is also a potential biomarker for a variety of diseases. For example, research has suggested that high levels of TNK1 may be associated with an increased risk of certain cardiovascular diseases, such as heart failure and stroke.

Furthermore, TNK1 has also been shown to be involved in the regulation of the immune system, which makes it an attractive target for drugs that are designed to enhance or modulate the immune response.

Overall, TNK1 is a protein that has a wide range of potential applications as a drug target and biomarker. Its role in the regulation of pain, inflammation, and cell growth, as well as its potential as a biomarker for a variety of diseases, make it an attractive target for further research and development.

Protein Name: Tyrosine Kinase Non Receptor 1

Functions: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction

The "TNK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TNK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TNK2 | TNK2-AS1 | TNKS | TNKS1BP1 | TNKS2 | TNMD | TNN | TNNC1 | TNNI1 | TNNI2 | TNNI3 | TNNI3K | TNNT1 | TNNT2 | TNNT3 | TNP1 | TNP2 | TNPO1 | TNPO2 | TNPO3 | TNR | TNRC17 | TNRC18 | TNRC18P1 | TNRC6A | TNRC6B | TNRC6C | TNS1 | TNS1-AS1 | TNS2 | TNS2-AS1 | TNS3 | TNS4 | TNXA | TNXB | TOB1 | TOB1-AS1 | TOB2 | TOB2P1 | TODL | TOE1 | TOGARAM1 | TOGARAM2 | Toll-Like Receptor | TOLLIP | TOLLIP-DT | Tolloid-like protein | TOM complex | TOM1 | TOM1L1 | TOM1L2 | TOMM20 | TOMM20L | TOMM20P2 | TOMM22 | TOMM34 | TOMM40 | TOMM40L | TOMM40P2 | TOMM5 | TOMM6 | TOMM7 | TOMM70 | Tomoregulin | TONSL | TONSL-AS1 | TOP1 | TOP1MT | TOP1P1 | TOP1P2 | TOP2A | TOP2B | TOP3A | TOP3B | TOP3BP1 | TOPAZ1 | TOPBP1 | TOPORS | TOR1A | TOR1AIP1 | TOR1AIP2 | TOR1B | TOR2A | TOR3A | TOR4A | TOX | TOX2 | TOX3 | TOX4 | TP53 | TP53AIP1 | TP53BP2 | TP53I11 | TP53I13 | TP53I3 | TP53INP1 | TP53INP2 | TP53RK | TP53TG1 | TP53TG3