TNRC6B: A Repeat Mutation of Interest as A Drug Target Or Biomarker

Target Name: TNRC6B

NCBI ID: G23112

TNRC6B

TNRC6B: A Repeat Mutation of Interest as A Drug Target Or Biomarker

Trinucleotide repeat containing 6B (TNRC6B) is a stretch of DNA that is repeated three times in a gene. It is a common genetic variation that has been identified in a variety of organisms, including humans. While it is not known for certain functions, it is possible that TNRC6B may be a drug target or biomarker.

The TNRC6B repeat is a stretch of DNA that is located on chromosome 16. It is characterized by a repeated sequence of the nucleotides ACG, which is then followed by a variable number of additional nucleotides. This repeated sequence is located in the gene responsible for the protein encoded by the gene, which is involved in a variety of cellular processes.

One of the reasons why TNRC6B is of interest as a drug target is that it is highly conserved across different species. This suggests that any changes in the gene expression or function of the protein encoded by the gene may be important for the function of the gene in different organisms. This may make it an attractive target for drugs that are designed to modulate the activity of the gene.

In addition, the fact that TNRC6B is repeated in multiple copies suggests that it may be involved in the regulation of gene expression. This is because the repeated sequence may be involved in the formation of RNA molecules that are translationally processed to create proteins. It is possible that these RNA molecules play a role in the regulation of gene expression, and that changes in their levels or activity may be important for the function of the gene.

Another potential mechanism by which TNRC6B may be involved in the regulation of gene expression is its role in the development and progression of cancer. The repeated sequence is thought to be involved in the regulation of the cell cycle, which is a critical process in the development and progression of cancer. This may be because changes in the cell cycle regulation by the gene are associated with the development of cancer.

It is also possible that TNRC6B may be involved in the regulation of cellular processes that are important for the development and maintenance of the immune system. The immune system is a critical system that is involved in protecting the body against infection and disease, and it is possible that changes in the regulation of the immune system by the gene may be important for the function of the immune system.

In conclusion, TNRC6B is a stretch of DNA that is repeated three times in a gene. While it is not known for certain functions, it is possible that it may be a drug target or biomarker. Further research is needed to determine the exact role of TNRC6B in the regulation of gene expression and cellular processes.

Protein Name: Trinucleotide Repeat Containing Adaptor 6B

Functions: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs) (PubMed:16289642, PubMed:19167051, PubMed:19304925, PubMed:32354837). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins (PubMed:16289642, PubMed:19167051, PubMed:19304925, PubMed:32354837). As scaffolding protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes (PubMed:21981923)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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