LHX4: A Potential Drug Target and Biomarker (G89884)

Target Name: LHX4

NCBI ID: G89884

LHX4

LHX4: A Potential Drug Target and Biomarker

LHX4 (OTTHUMP00000033083) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in response to increased temperatures, such as those that occur during exercise or infection.

One of the functions of LHX4 is to regulate the expression of other genes. This is done by interacting with the DNA-binding proteins known as transcription factors. Transcription factors are proteins that bind to specific DNA sequences and regulate the expression of the genes that are associated with those sequences.

LHX4 has been shown to play a role in the regulation of gene expression in a variety of organisms, including humans. For example, studies have shown that LHX4 can interact with the transcription factor p53, and that this interaction can modulate the expression of genes involved in cell division, apoptosis, and inflammation.

In addition to its role in gene regulation, LHX4 has also been shown to play a role in the regulation of protein structure and function. This is done by interacting with a variety of protein partners, including other heat shock proteins and transcription factors.

The protein encoded by the LHX4 gene is 44 kilobases (kb) long and has a calculated molecular weight of 49.9 kdas. It is expressed in a variety of tissues and cells, including the brain, heart, kidneys, and liver. It is also highly Conservative, with only one amino acid change identified between the gene and its protein product.

While more research is needed, the potential implications of LHX4 as a drug target are significant. Given its role in gene regulation and protein structure and function, LHX4 could be a valuable target for the development of new therapeutic strategies for a variety of diseases. For For example, LHX4 could be used to treat neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, as well as to treat a variety of other conditions including cancer, inflammation, and infection.

In addition to its potential therapeutic applications, LHX4 also has the potential to serve as a biomarker for a variety of diseases. Given its role in the regulation of gene expression and protein structure and function, LHX4 could be used as a marker for a variety of diseases, including but not limited to cancer, neurodegenerative diseases, and infections.

Overall, LHX4 is a protein that has the potential to be a valuable drug target and biomarker for a variety of diseases. Further research is needed to fully understand its functions and to develop new strategies for the treatment of a variety of conditions.

Protein Name: LIM Homeobox 4

Functions: May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DNA (PubMed:28473536)

The "LHX4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LHX4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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