LRSAM1: A Protein with Unique Biology and Potential as A Drug Target

Target Name: LRSAM1

NCBI ID: G90678

LRSAM1

LRSAM1: A Protein with Unique Biology and Potential as A Drug Target

LRSAM1 (LRSAM1 variant 1) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Leucine-rich repeat adaptor protein (LRSAM) family, which is a group of transmembrane proteins that are characterized by the presence of a leucine-rich repeat in their extracellular domain.

LRSAM1 is unique among its family members due to its ability to form a monomeric species in solution, a phenomenon that is not observed in many other LRSAM proteins. This monomeric state has been shown to affect the structure and function of LRSAM1, and may play a role in its unique biology.

In addition to its unique monomeric state, LRSAM1 has also been shown to be involved in a number of cellular processes that are important for its function. For example, LRSAM1 has been shown to play a role in the regulation of protein translation, which is the process by which cells translate the information in their DNA into the proteins that they need to function.

LRSAM1 has also been shown to be involved in the regulation of cellular signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and maintenance of tissues and organs.

In addition to its role in cellular signaling, LRSAM1 has also been shown to be involved in the regulation of cellular memory and learning. This is an important function for LRSAM1, as the ability to remember and learn is a key aspect of brain function.

Given its unique biology and its involvement in a number of important cellular processes, LRSAM1 is a promising drug target for researchers. Studies have shown that LRSAM1 can be targeted with small molecules, and that this can lead to the inhibition of its function. This suggests that LRSAM1 may be a useful target for the development of new therapies for a variety of diseases.

In conclusion, LRSAM1 is a protein that is expressed in various tissues of the body and is involved in a number of important cellular processes. Its unique monomeric state and its involvement in the regulation of protein translation, cellular signaling pathways, and cellular memory and learning make it a promising drug target for researchers. Further studies are needed to fully understand the function of LRSAM1 and its potential as a drug target.

Protein Name: Leucine Rich Repeat And Sterile Alpha Motif Containing 1

Functions: E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098)

The "LRSAM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LRSAM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets