ARRDC4: A Protein Implicated in Various Diseases (G91947)

Target Name: ARRDC4

NCBI ID: G91947

ARRDC4

Other Name(s): Arrestin domain containing 4 | ARRD4_HUMAN | FLJ36045 | arrestin domain containing 4 | Arrestin domain-containing protein 4

ARRDC4: A Protein Implicated in Various Diseases

Arrestin domain containing 4 (ARRDC4) is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell-cell adhesion and has been implicated in various diseases, including cancer.

ARRDC4 is composed of four distinct domains: an N-terminal transmembrane domain, a coiled-coil domain, a variable region, and a C-terminal T-cell receptor (TCR) alpha chain-like domain. The N-terminal transmembrane domain is responsible for the protein's ability to enter the cell and for its structural stability. The coiled-coil domain is responsible for the protein's ability to form helices, which can modulate its stability and function.

The variable region of ARRDC4 is the region that is involved in its unique structure and function. It is composed of a series of distinct regions that give the protein its unique 3D structure. The variable region plays a critical role in regulating the interactions between the protein and its downstream targets.

The C-terminal T-cell receptor (TCR) alpha chain-like domain is the region that is responsible for the protein's ability to recognize and interact with TCR alpha chains. This domain is composed of a series of distinct regions that give the protein its unique structure and function.

ARRDC4 is a protein that has been shown to play a critical role in various diseases, including cancer. It is involved in the regulation of cell-cell adhesion, which is a critical process that helps maintain tissue structure and function.

ARRDC4 is also involved in the regulation of cell proliferation. It has been shown to play a critical role in the regulation of cell proliferation, and it is thought to do so by regulating the interactions between the protein and its downstream targets.

ARRDC4 is also involved in the regulation of cell differentiation. It has been shown to play a critical role in the regulation of cell differentiation, and it is thought to do so by regulating the interactions between the protein and its downstream targets.

In conclusion, Arrestin domain containing 4 (ARRDC4) is a protein that is involved in a variety of critical processes in the body. It is a potential drug target and may be a useful biomarker for various diseases. Further research is needed to fully understand the role of ARRDC4 in the regulation of cell-cell adhesion, cell proliferation, and cell differentiation.

Protein Name: Arrestin Domain Containing 4

Functions: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (By similarity). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles (By similarity). May play a role in glucose uptake (PubMed:19605364). Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65 (PubMed:28594402)

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