Target Name: ASPG
NCBI ID: G374569
Review Report on ASPG Target / Biomarker Content of Review Report on ASPG Target / Biomarker
ASPG
Other Name(s): L-asparaginase | lysophospholipase-transacylase | PAF acetylhydrolase | Asparaginase | Wild-type L-asparaginase | LPP60_HUMAN | 1-alkyl-2-acetylglycerophosphocholine esterase | asparaginase homolog | LysoLP | Lysophospholipase-transacylase | hASNase1 | asparaginase | Platelet-activating factor acetylhydrolase | C14orf76 | LYSOLP | GPA/WT | L-asparagine amidohydrolase | 60 kDa lysophospholipase | wild-type L-asparaginase

ASPG: A Promising Drug Target and Biomarker

ASPG, or L-asparaginase, is a drug target and biomarker that is currently being studied for its potential therapeutic uses. Asparaginase is an enzyme that is involved in the metabolism of asparagin, a compound that is found in many proteins, including those that are involved in cell signaling pathways.

ASPG is being studied for its potential to treat a variety of conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. It is believed that ASPG can inhibit the activity of cancer cells, leading to a reduction in cell proliferation and the formation of new tumors.

In addition to its potential as a cancer treatment, ASPG is also being studied for its potential to treat other conditions. For example, it is being investigated as a potential treatment for neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, as well as for autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

ASPG is also being studied as a potential biomarker for a variety of conditions. For example, it is being used to assess the effectiveness of certain treatments, such as cancer treatments, as well as to monitor the progress of neurodegenerative diseases.

Despite the potential benefits of ASPG, there are also concerns about its potential side effects. Some studies have suggested that ASPG can cause side effects, such as nausea, vomiting, and diarrhea, in certain individuals. However, these side effects are generally considered to be mild and do not typically lead to significant harm to patients.

Overall, ASPG is a drug target and biomarker that is being studied for its potential therapeutic uses. While more research is needed to fully understand its effects and to determine its safety and efficacy, it holds promise as a treatment for a variety of conditions.

Protein Name: Asparaginase

Functions: Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities (By similarity). Can catalyze three types of transacylation reactions: (1) acyl transfer from 1-acyl-sn-glycero-3-phosphocholine (1-acyl-GPC) to the sn-1(3) positions of glycerol and 2-acylglycerol (sn-1 to -1(3) transfer), (2) acyl transfer from 1-acyl-GPC to the sn-2 positions of 1-acyl-GPC, 1-acyl-sn-glycero-3-phosphoethanolamine (1-acyl-GPE), and other lysophospholipids (sn-1 to -2 transfer) and (3) acyl transfer from 2-acyl-GPC to the sn-1 position of 2-acyl-GPC and 2-acyl-GPE (sn-2 to -1 transfer) (By similarity). Mediates the synthesis of 1-arachidonoyl species of phospholipids by transferring the arachidonoyl residue from 2-arachidonoyl lysophospholipid to the sn-1 position of 2-acyl lysophospholipid (By similarity)

The "ASPG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ASPG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ASPH | ASPHD1 | ASPHD2 | ASPM | ASPN | ASPRV1 | ASPSCR1 | ASRGL1 | ASS1 | ASS1P1 | ASS1P10 | ASS1P11 | ASS1P12 | ASS1P13 | ASS1P2 | ASS1P4 | ASS1P5 | ASS1P6 | ASS1P7 | ASS1P9 | ASTE1 | ASTL | ASTN1 | ASTN2 | ASTN2-AS1 | Astrin complex | ASXL1 | ASXL2 | ASXL3 | ASZ1 | AT-Rich interactive domain-containing protein | ATAD1 | ATAD2 | ATAD2B | ATAD3A | ATAD3B | ATAD3C | ATAD5 | ATAT1 | ATCAY | ATE1 | ATE1-AS1 | ATF1 | ATF2 | ATF3 | ATF4 | ATF4P2 | ATF4P4 | ATF5 | ATF6 | ATF6-DT | ATF6B | ATF7 | ATF7IP | ATF7IP2 | ATG10 | ATG101 | ATG12 | ATG13 | ATG14 | ATG16L1 | ATG16L2 | ATG2A | ATG2B | ATG3 | ATG4A | ATG4B | ATG4C | ATG4D | ATG5 | ATG7 | ATG9A | ATG9B | ATIC | ATL1 | ATL2 | ATL3 | ATM | ATMIN | ATN1 | ATOH1 | ATOH7 | ATOH8 | ATOSA | ATOSB | ATOX1 | ATOX1-AS1 | ATP Synthase, H+ Transporting, Mitochondrial F0 complex | ATP synthase, H+ transporting, mitochondrial F1 complex | ATP-Binding Cassette (ABC) Transporter | ATP-dependent 6-phosphofructokinase | ATP10A | ATP10B | ATP10D | ATP11A | ATP11A-AS1 | ATP11AUN | ATP11B | ATP11C | ATP12A