ARX: A Potential Drug Target and Biomarker (G170302)

Target Name: ARX

NCBI ID: G170302

Content of Review Report on ARX Target / Biomarker

ARX

Other Name(s): aristaless related homeobox | MRX38 | MRX87 | Aristaless-related homeobox, X-linked | cancer/testis antigen 121 | Infantile spasm syndrome, X-linked | Aristaless-related homeobox | ISSX | PRTS | aristaless-related homeobox, X-linked | CT121 | Homeobox protein ARX | MRX54 | ARX_HUMAN | MRX29 | MRX36 | EIEE1 | MRX43 | Aristaless related homeobox | MRX33 | MRX76 | MRX32 | MRXS1

ARX: A Potential Drug Target and Biomarker

ARX is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is involved in the regulation of cellular processes that are essential for maintaining cellular health and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, ARX has emerged as a promising drug target and biomarker for a variety of therapeutic approaches.

The Discovery of ARX

The discovery of ARX was made through a combination of biochemical, cellular, and animal studies. Researchers found that ARX was expressed in a variety of tissues and that it was involved in the regulation of cellular processes that are critical for maintaining cellular health. They also found that ARX was overexpressed in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The Potential Functions of ARX

ARX is involved in a number of cellular processes that are essential for maintaining cellular health. These processes include cell signaling, cell division, and cell survival. ARX is also involved in the regulation of cellular processes that are critical for the development and maintenance of tissues, including the regulation of cell migration and the regulation of cell proliferation.

ARX is also involved in the regulation of cellular processes that are critical for the regulation of the immune system. It is expressed in the immune cells and it plays an important role in the regulation of the immune response.

The Potential Therapeutic Applications of ARX

The potential therapeutic applications of ARX are vast and varied. Because ARX is involved in so many cellular processes that are essential for maintaining cellular health, it is a promising target for a variety of therapeutic approaches.

One of the potential therapeutic applications of ARX is as a cancer therapeutic. Because ARX is overexpressed in a variety of cancers, it is a potential target for cancer therapies. For example, ARX has been shown to be downregulated in many types of cancer, including breast, ovarian, and colorectal cancers. Therefore, ARX may be an effective cancer therapeutic by inhibiting its expression in cancer cells.

Another potential therapeutic application of ARX is as a neurodegenerative disease therapeutic. Because ARX is involved in the regulation of cellular processes that are critical for maintaining cellular health, it is a potential target for neurodegenerative diseases. For example, ARX has been shown to be involved in the regulation of the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Therefore, ARX may be an effective neurodegenerative disease therapeutic by inhibiting its expression in neurodegenerative disease cells.

In addition to its potential therapeutic applications, ARX is also a potential biomarker for a variety of diseases. Because ARX is overexpressed in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders, it may be a useful biomarker for these diseases. For example, ARX has been shown to be elevated in the blood of patients with breast, ovarian, and colorectal cancers. Therefore, ARX may be a useful biomarker for these cancers.

The Identification of ARX as a Drug Target

The identification of ARX as a drug target is based on a combination of biochemical, cellular, and animal studies. These studies have provided evidence that ARX is involved in the regulation of cellular processes that are essential for maintaining cellular health and that it is involved in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The Identification of ARX as a Potential Drug Target

The identification of ARX as a potential drug target was based on a combination of biochemical, cellular, and animal studies. These studies provided evidence that ARX is involved in the regulation of cellular processes that are essential for maintaining cellular health and that it is involved in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

ARX is involved in the regulation of cell signaling, cell division, and cell survival. It is also involved in the regulation of cellular processes that are critical for

Protein Name: Aristaless Related Homeobox

Functions: Transcription factor (PubMed:22194193, PubMed:31691806). Binds to specific sequence motif 5'-TAATTA-3' in regulatory elements of target genes, such as histone demethylase KDM5C (PubMed:22194193, PubMed:31691806). Positively modulates transcription of KDM5C (PubMed:31691806). Activates expression of KDM5C synergistically with histone lysine demethylase PHF8 and perhaps in competition with transcription regulator ZNF711; synergy may be related to enrichment of histone H3K4me3 in regulatory elements (PubMed:31691806). Required for normal brain development (PubMed:11889467, PubMed:12379852, PubMed:14722918). Plays a role in neuronal proliferation, interneuronal migration and differentiation in the embryonic forebrain (By similarity). May also be involved in axonal guidance in the floor plate (By similarity)

The "ARX Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARX comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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