The Dombrock Blood Group Carrier Molecule: A Key Protein in The Immune System

Target Name: ART4

NCBI ID: G420

ART4

The Dombrock Blood Group Carrier Molecule: A Key Protein in The Immune System

The Blood Group System, also known as the ABO blood group system, is a natural occurrence in human blood that is responsible for differentiating one individual from another. The system is based on the presence or absence of certain antigens on the surface of red blood cells . These antigens are called antigens, and the antibodies that are produced in response to them are called antibodies. There are four main blood groups: A, B, AB, and O. Each group has its own unique antigens and corresponding antibodies.

One of the proteins that is responsible for the formation of these antibodies is the Dombrock blood group carrier molecule. It is a carrier protein that is found on the surface of red blood cells and helps to facilitate the formation of antibodies in response to the presence of certain antigens.

The Dombrock blood group carrier molecule is made up of four subunits: a heavy chain and three light chains. The heavy chain consists of 126 amino acids, while the light chains consist of 64 amino acids. These subunits are held together by disulfide bonds, and the entire molecule has a calculated molecular weight of 17.9 kDa.

The Dombrock blood group carrier molecule is able to bind to certain antigens, such as the red blood cell antigens GP and Hp, as well as the cell surface antigens GPb and Hpb. When the Dombrock blood group carrier molecule binds to an antigen, it helps to facilitate the formation of a properly functioning antibody.

One of the unique features of the Dombrock blood group carrier molecule is its ability to self-clearer. This means that, after it has helped to form an antibody, the molecule can be removed from the body by the immune system. This allows the immune system to remember that the Dombrock blood group carrier molecule is no longer present and to continue to produce antibodies in response to its presence.

In addition to its role in the formation of antibodies, the Dombrock blood group carrier molecule may also be a drug target or biomarker. For example, if the Dombrock blood group carrier molecule is found to be an attractive target for drug development, it may be used to treat autoimmune disorders or other conditions that involve an overactive immune system. Additionally, the Dombrock blood group carrier molecule may be used as a biomarker to diagnose diseases or to monitor the effectiveness of treatments.

Overall, the Dombrock blood group carrier molecule is an important protein that plays a critical role in the immune system. Its ability to facilitate the formation of antibodies and its self-clearing properties make it an attractive target for drug development and a useful biomarker for diagnostics and monitoring a wide range of diseases.

Protein Name: ADP-ribosyltransferase 4 (inactive) (Dombrock Blood Group)

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