Target Name: ASCL4
NCBI ID: G121549
Review Report on ASCL4 Target / Biomarker Content of Review Report on ASCL4 Target / Biomarker
ASCL4
Other Name(s): ASCL4_HUMAN | Achaete-scute homolog 4 | class II bHLH protein ASCL4 | ASH-4 | Achaete-scute family bHLH transcription factor 4 | Class A basic helix-loop-helix protein 44 | class A basic helix-loop-helix protein 44 | achaete-scute complex homolog 4 | Achaete-scute complex-like 4 | achaete-scute-like protein 4 | achaete-scute complex-like 4 | achaete-scute family bHLH transcription factor 4 | HASH4 | hASH4 | bHLHa44 | Class II bHLH protein ASCL4 | Achaete-scute-like protein 4

ASCL4: A Potential Drug Target and Biomarker for the Treatment of Cancer

Abstract:

ASCL4 is a gene that encodes a protein known as ASCL4, which has been shown to play a critical role in various cellular processes, including cell growth, apoptosis, and angiogenesis. The ASCL4 protein has also been associated with the development and progression of various types of cancer. Therefore, ASCL4 has potential as a drug target and biomarker for cancer treatment. This article will discuss the biology of ASCL4, its functions in cancer, and its potential as a drug target and biomarker.

Introduction:

Cancer is a leading cause of death worldwide, with over 20 million new cases being diagnosed every year. The development and progression of cancer is a complex process that involves the interplay of multiple genetic and epigenetic factors. One of the key factors that have been identified in the development of cancer is the over-expression of various genes, including ASCL4.

ASCL4: A Putative Drug Target:

ASCL4 is a gene that encodes a protein known as ASCL4. The ASCL4 protein has been shown to play a critical role in various cellular processes, including cell growth, apoptosis, and angiogenesis. It is a member of the FERMT (Fusiform Enrichment of Retinoblastoma- Controlled Tetrandric Acid-Napped) family, which is known for its role in cell-cell adhesion and other processes that involve actinin.

ASCL4 has been shown to be involved in the regulation of various cellular processes, including cell growth, apoptosis, and angiogenesis. It has been shown to play a critical role in the development and progression of various types of cancer, including breast, ovarian, and colorectal cancers.

ASCL4 as a Biomarker:

ASCL4 has also been shown to be involved in the regulation of various cellular processes, including cell growth, apoptosis, and angiogenesis. It has been shown to be a potential biomarker for cancer, as it has been shown to be over-expressed in various types of cancer. This suggests that ASCL4 may be a useful target for cancer treatment, as drugs that can reduce ASCL4 expression may have potential therapeutic effects.

ASCL4 as a Drug Target:

ASCL4 has been shown to play a critical role in the development and progression of various types of cancer, including breast, ovarian, and colorectal cancers. Therefore, ASCL4 has potential as a drug target for cancer treatment.

One approach to targeting ASCL4 as a drug target is to use small molecules that can inhibit its expression or activity. This approach has been used to develop drugs that target various proteins involved in cancer development, including ASCL4.

Conclusion:

ASCL4 is a gene that encodes a protein that has been shown to play a critical role in various cellular processes, including cell growth, apoptosis, and angiogenesis. Its over-expression has been associated with the development and progression of various types of cancer. Therefore , ASCL4 has potential as a drug target and biomarker for cancer treatment. The use of small molecules that can inhibit ASCL4 expression or activity may be a promising approach to cancer treatment. Further research is needed to fully understand the role of ASCL4 in cancer and to develop effective treatments.

Protein Name: Achaete-scute Family BHLH Transcription Factor 4

Functions: Could be a transcriptional regulator involved in skin development

The "ASCL4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ASCL4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ASCL5 | ASF1A | ASF1B | ASGR1 | ASGR2 | ASH1L | ASH1L-AS1 | ASH2L | Asialoglycoprotein receptor | Asialoglycoprotein Receptor (ASGPR) | ASIC1 | ASIC2 | ASIC3 | ASIC4 | ASIC5 | ASIP | ASL | ASMER1 | ASMER2 | ASMT | ASMTL | ASMTL-AS1 | ASNS | ASNSD1 | ASNSP1 | ASPA | ASPDH | ASPG | ASPH | ASPHD1 | ASPHD2 | ASPM | ASPN | ASPRV1 | ASPSCR1 | ASRGL1 | ASS1 | ASS1P1 | ASS1P10 | ASS1P11 | ASS1P12 | ASS1P13 | ASS1P2 | ASS1P4 | ASS1P5 | ASS1P6 | ASS1P7 | ASS1P9 | ASTE1 | ASTL | ASTN1 | ASTN2 | ASTN2-AS1 | Astrin complex | ASXL1 | ASXL2 | ASXL3 | ASZ1 | AT-Rich interactive domain-containing protein | ATAD1 | ATAD2 | ATAD2B | ATAD3A | ATAD3B | ATAD3C | ATAD5 | ATAT1 | ATCAY | ATE1 | ATE1-AS1 | ATF1 | ATF2 | ATF3 | ATF4 | ATF4P2 | ATF4P4 | ATF5 | ATF6 | ATF6-DT | ATF6B | ATF7 | ATF7IP | ATF7IP2 | ATG10 | ATG101 | ATG12 | ATG13 | ATG14 | ATG16L1 | ATG16L2 | ATG2A | ATG2B | ATG3 | ATG4A | ATG4B | ATG4C | ATG4D | ATG5 | ATG7 | ATG9A