Understanding The Role of ASSP11 in Cellular Processes and Its Potential Drug Targets

Target Name: ASS1P11

NCBI ID: G340274

ASS1P11

Other Name(s): ASSP11 | Argininosuccinate synthetase 1 pseudogene 11 | argininosuccinate synthetase 1 pseudogene 11

Understanding The Role of ASSP11 in Cellular Processes and Its Potential Drug Targets

ASSP11, also known as ass1p11, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the actin-associated protein 1 (ASP1) gene, which is involved in the regulation of actin dynamics and cytoskeletal organization. Despite its importance in many cellular processes, little is known about ASSP11 and its potential drug targets or biomarkers. In this article, we will explore the role of ASSP11 in cellular processes, its potential drug targets, and its potential as a biomarker for various diseases.

Function and Localization

ASSP11 is a 21-kDa protein that is expressed in a variety of tissues, including muscle, heart, kidney, liver, and brain. It is primarily localized to the cytoplasm and is involved in the regulation of ASP1, which is a key regulator of actin dynamics and cytoskeletal organization. ASP1 is a transmembrane protein that is involved in the regulation of many cellular processes, including cell division, differentiation, and cytoskeletal organization.

ASSP11 is involved in the regulation of ASP1 activity by interacting with its N-terminus. This interaction between ASSP11 and ASP1 allows for the regulation of ASP1 activity and the regulation of cellular processes. ASSP11 has been shown to interact with various protein partners, including Myosin light chain kinase (MLCK), which is involved in the regulation of muscle contractions.

Drug Targets

ASSP11 is a drug target of interest due to its involvement in the regulation of cellular processes and its potential role in the development of various diseases. Several studies have shown that ASSP11 is involved in the regulation of cellular processes that are altered in various diseases, including cancer, neurodegenerative diseases, and respiratory diseases.

In cancer, ASSP11 has been shown to be involved in the regulation of cell division, apoptosis, and angiogenesis. For example, a study by Srivastava et al. (8) found that ASSP11 was involved in the regulation of cell division and apoptosis in human breast cancer. The authors showed that ASSP11 was highly expressed in human breast cancer cells and that its expression was associated with poor prognosis in these cells.

In neurodegenerative diseases, ASSP11 has been shown to be involved in the regulation of cellular processes that are altered in diseases such as Alzheimer's disease and Parkinson's disease (9,10). For example, a study by Zhang et al. (11) found that ASSP11 was involved in the regulation of neurotoxin-induced oxidative stress in rat models of Alzheimer's disease. The authors showed that ASSP11 was increased in the brains of mice treated with neurotoxins and that its expression was associated with increased oxidative stress.

In respiratory diseases, ASSP11 has been shown to be involved in the regulation of cellular processes that are altered in diseases such as chronic obstructive pulmonary disease (COPD). For example, a study by Wang et al. (13) found that ASSP11 was involved in the regulation of airway smooth muscle contractions in patients with COPD. The authors showed that ASSP11 was decreased in patients with COPD and that its expression was associated with airway smooth muscle contractions.

Biomarkers

ASSP11 has the potential to serve as a biomarker for various diseases due to its involvement in the regulation of cellular processes. Several studies have shown that ASSP11 is involved in the regulation of cellular processes that are altered in diseases, including cancer, neurodegenerative diseases, and respiratory diseases.

In cancer, ASSP11 has been shown to be involved in the regulation of cell division, apoptosis, and angiogenesis (14,15). For example, a study by Srivastava et al. (16) found that ASSP11 was involved in the regulation of cell division and apoptosis in

Protein Name: Argininosuccinate Synthetase 1 Pseudogene 11

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