DSEL: A Protein Involved in Cell Growth, Differentiation and Cancer Development

Target Name: DSEL

NCBI ID: G92126

DSEL

DSEL: A Protein Involved in Cell Growth, Differentiation and Cancer Development

DSEL (Dermatan-sulfate epimerase-like protein) is a protein that is expressed in various tissues throughout the body, including the skin, hair, nails, and bones. It is a member of the evolutionarily conserved DSPP (DNA-binding protein) gene family, which includes a variety of proteins that play important roles in various cellular processes, including DNA replication, repair, and epigenetic modulation.

DSEL is a 25kDa protein that is composed of 156 amino acid residues. It has a unique structure that is characterized by a long N-terminus that contains a putative N-endonuclease domain, as well as a short C-terminus that contains a potential G-protein-coupled receptor (GPCR) domain. The N-endonuclease domain is a characteristic feature of proteins that are involved in DNA-binding and repair, and the C-terminus is a common domain found in GPCR proteins that are involved in signaling and signaling interactions.

DSEL is expressed in a variety of tissues and cells throughout the body, including the skin, hair, nails, and bones. It is highly expressed in the skin, where it is found in the epidermis, dermis, and sweat glands. It is also expressed in the hair and nails, where it plays a role in the growth and maintenance of these tissues. In addition, DSL (Dermatan sulfate leukotriene) homolog 2 (DSL2) is a closely related gene that is also expressed in hair and nails, and it is involved in the production of dermatan sulfate, which is a potent vasodilator and emollient.

DSEL has been shown to play a role in various cellular processes, including cell growth, differentiation, and inflammation. For example, it has been shown to be involved in the regulation of cell proliferation and differentiation, as well as in the development of cancer. It has also been shown to play a role in the regulation of inflammation and immune responses, as well as in the regulation of pain.

DSEL is a potential drug target and may be a useful biomarker for the diagnosis and treatment of various diseases. For example, it has been shown to be involved in the development of skin cancer, including squamous cell carcinoma (SCC), and it may be a useful biomarker for the detection and prognosis of SCC. It has also been shown to be involved in the development of other cancers, including lung cancer and colon cancer, and it may be a useful biomarker for the detection and prognosis of these cancers.

In addition to its potential as a drug target, DSL2 has also been shown to be involved in the regulation of various physiological processes, including blood clotting, angiogenesis, and inflammation. It has been shown to interact with a variety of proteins, including the protein tyrosine phosphatase (PTP) 2 (PTP2), which is involved in the regulation of many cellular processes, including cell growth, differentiation, and inflammation.

In conclusion, DSL2 (DSEL) is a protein that is expressed in various tissues throughout the body, including the skin, hair, nails, and bones. It is a member of the DSPP gene family and has a unique structure that is characterized by a long N-terminus that contains a putative N-endonuclease domain, as well as a short C-terminus that contains a potential G-protein-coupled receptor (GPCR) domain. DSL2 has been shown to play a role in various cellular processes, including cell growth, differentiation, and inflammation, and it may be a useful drug target and biomarker for the diagnosis and treatment of various diseases. Further research is needed to fully understand the role of DSL2 in these processes and to develop effective therapies based on it.

Protein Name: Dermatan Sulfate Epimerase Like

The "DSEL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DSEL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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