CYTH3: A Protein Targeted for Cancer and Other Diseases (G9265)

Target Name: CYTH3

NCBI ID: G9265

CYTH3

CYTH3: A Protein Targeted for Cancer and Other Diseases

CYTH3, also known as cytohesin-3, is a protein that is expressed in various cell types of the human body. It is a member of the cytoheme family, which are a type of protein that contains a central heme atom that is fused to a cytoplasmic tail. CYTH3 is involved in a variety of cellular processes, including cell signaling, DNA replication, and response to stress.

One of the unique features of CYTH3 is its ability to interact with other proteins. It has been shown to form a complex with the protein Noxa, which is involved in cell signaling and stress response. This interaction between CYTH3 and Noxa has been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

Another promising aspect of CYTH3 is its potential as a drug target. Its interaction with Noxa, as well as its involvement in cell signaling and stress response, make it a promising target for small molecules that can modulate these processes. This has led to a number of research studies aimed at identifying and developing compounds that can interact with CYTH3 and Noxa to enhance their therapeutic effects.

One approach to targeting CYTH3 is to use small molecules that can modulate its activity. One class of compounds that have been shown to interact with CYTH3 is called phthalonitrile derivatives. These compounds are derived from natural products such as pyridostigmine and tripyridostigmine, and have been shown to inhibit the activity of CYTH3 in cell experiments.

Another approach to targeting CYTH3 is to use drugs that can modulate its expression. One class of drugs that have been shown to do this is called inhibitors of DNA replication. These drugs work by inhibiting the activity of the enzyme DNA polymerase, which is essential for the replication of DNA in cells. By inhibiting DNA replication, these drugs can disrupt the growth and proliferation of cancer cells, which can be a potential mechanism of their therapeutic effects.

Another potential mechanism of CYTH3's targeting is its role in cell signaling. CYTH3 is involved in a number of signaling pathways, including the regulation of cell growth, apoptosis, and stress response. Drugs that can modulate these processes, such as inhibitors of the protein kinase PDK4, have been shown to be effective in cancer treatment.

In conclusion, CYTH3 is a protein that is involved in a number of cellular processes and has been shown to play a role in cancer and other diseases. Its ability to interact with other proteins and its potential as a drug target make it an attractive target for small molecules that can modulate its activity. Further research is needed to fully understand the mechanisms of its action and its potential as a therapeutic agent.

Protein Name: Cytohesin 3

Functions: Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity)

The "CYTH3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CYTH3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets