DDX23: A Member of The X-linked Inhibitor of DNA Binding Gene Family

Target Name: DDX23

NCBI ID: G9416

DDX23

DDX23: A Member of The X-linked Inhibitor of DNA Binding Gene Family

DDX23 (U5-100KD) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. It is a member of the X-linked inhibitor of DNA binding (XI) gene family, which is a family of proteins that play a critical role in regulating gene expression and DNA replication.

The XI gene family is characterized by the presence of a short N-terminal alpha helix, a long alpha helix in the middle, and a C-terminal alpha-helices region. The N-terminal region contains a putative RNA binding domain (RBS ), which is known to be involved in RNA binding and may function as a binding site for transcription factors. The middle region contains a long 伪-helix, which is known to be involved in the regulation of protein stability and structure. The C -Terminal region contains multiple conserved acidic residues, which may be involved in protein-protein interactions and other cellular processes.

DDX23 is a 23-kDa protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. It is a member of the X-linked inhibitor of DNA binding (XI) gene family, which is a family of proteins that play a critical role in regulating gene expression and DNA replication.

The XI gene family is characterized by the presence of a short N-terminal alpha helix, a long alpha helix in the middle, and a C-terminal alpha-helices region. The N-terminal region contains a putative RNA binding domain (RBS ), which is known to be involved in RNA binding and may function as a binding site for transcription factors. The middle region contains a long 伪-

Protein Name: DEAD-box Helicase 23

Functions: Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation (PubMed:18425142). Independently of its spliceosome formation function, required for the suppression of incorrect R-loops formed during transcription; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA (PubMed:28076779)

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