DDX49: A Drug Target / Disease Biomarker (G54555)

Target Name: DDX49

NCBI ID: G54555

DDX49

DDX49: A Drug Target / Disease Biomarker

DDX49 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the dynein gene family, which is responsible for the production of a family of proteins that play a role in the transport of organelles, including mitochondria, to the cytoplasm.

One of the unique aspects of DDX49 is its ability to interact with the protein T-tubulin. T-tubulin is a protein that is responsible for the proper assembly and disassembly of microtubules, which are important for the transport of organelles to the cytoplasm. By interacting with T-tubulin, DDX49 is able to regulate the movement of mitochondria to the cytoplasm, which is important for the proper function of the cell.

In addition to its role in regulating mitochondrial transport, DDX49 is also involved in the regulation of the stress response. When the cell experiences stress, it is able to respond by changing its shape and increasing its size. This increase in size is important for the cell to be able to respond to stress in a more effective manner.

DDX49 is also involved in the regulation of the actinin cytoskeleton. Actinin is a protein that is responsible for the proper organization of the cytoskeleton, which is important for the cell's shape and stability. By interacting with actinin, DDX49 is able to regulate the organization of the cytoskeleton, which is important for the cell's ability to respond to stress.

DDX49 is also involved in the regulation of the cell cycle. The cell cycle is the process by which a cell grows and replicates its DNA. By interacting with the protein p21, DDX49 is able to regulate the length of the cell cycle, which is important for the cell's ability to divide and replicate its DNA.

In addition to its role in regulating the cell cycle, DDX49 is also involved in the regulation of the apoptosis (programmed cell death) pathway. Apoptosis is a natural process that occurs when a cell is no longer able to divide and is programmed to die. By interacting with the protein Bcl-2, DDX49 is able to regulate the apoptosis pathway, which is important for the cell's ability to respond to stress and repair damage.

DDX49 is also involved in the regulation of the autophagy (self-cleaning) pathway. Autophagy is a process by which a cell breaks down and recycles its own damaged or unnecessary components. By interacting with the protein light atel, DDX49 is able to regulate the autophagy pathway, which is important for the cell's ability to respond to stress and repair damage.

In conclusion, DDX49 is a protein that is involved in a number of important processes in the cell. Its ability to interact with T-tubulin, actinin, and other cytoskeleton proteins makes it an important regulator of mitochondrial transport, the stress response, the cell cycle, apoptosis, and autophagy. These processes are important for the cell's ability to function and survive, and therefore DDX49 is a potential drug target (or biomarker) for the development of new therapies for a variety of diseases.

Protein Name: DEAD-box Helicase 49

The "DDX49 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DDX49 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets