Target Name: EFCAB13
NCBI ID: G124989
Review Report on EFCAB13 Target / Biomarker Content of Review Report on EFCAB13 Target / Biomarker
EFCAB13
Other Name(s): EF-hand calcium binding domain 13 | EF-hand calcium binding domain 13, transcript variant A | EFC13_HUMAN | EF-hand calcium-binding domain-containing protein 13 (isoform A) | EFCAB13 variant A | C17orf57 | EF-hand calcium-binding domain-containing protein 13 | EF-hand domain-containing protein C17orf57

Unlocking the Potential of EFCAB13: A Promising Drug Target and Biomarker

Introduction

The protein encoded by the gene EFCAB13 (EF-hand calcium binding domain 13) has been shown to play a critical role in various cellular processes, including cell signaling, protein-protein interactions, and DNA replication. Its domain has a special charge and three-dimensional structure, allowing it to interact with a variety of biological molecules such as DNA, RNA and proteins. In addition, EFCAB13 plays an important role in many fields such as the nervous system, endocrine system, and immune system, so it has high research and application value. This article will discuss the structure, function, drug targets and other aspects of EFCAB13, with a view to providing some new ideas and inspirations for researchers in related fields.

1. Structure and function of EFCAB13

EFCAB13 is a calcium ion-binding protein with a unique quaternary structure. It consists of 114 amino acids and contains a unique EF-hand domain. This domain has a special charge that enables it to form a stable bond with calcium ions. The secondary structure of EFCAB13 is mainly composed of two interacting 尾-helices and two parallel 伪-helices. This structure makes it highly compact and accessible in three-dimensional space.

The function of EFCAB13 is mainly reflected in its role as a signal transduction molecule. Within cells, EFCAB13 serves as a ligand that interacts with a variety of proteins, including DNA-binding complexes and molecules in intracellular signal transduction pathways. Through these interactions, EFCAB13 can participate in a variety of biological processes, such as cell proliferation, differentiation, and tumor formation. In addition, EFCAB13 can also specifically bind to certain drugs, making it a potential drug target.

2. Drug target properties of EFCAB13

As a functional protein, EFCAB13 has always been a focus of attention in the field of drug research and development. In recent years, researchers have speculated on the possible targets of EFCAB13 by combining bioinformatics methods. These targets include:

1. Calcium ion binding: EFCAB13 is a calcium ion-binding protein, and its unique EF-hand domain enables it to form a stable combination with calcium ions. Therefore, calcium ion binding may become a potential drug target.

2. Signal transduction: EFCAB13 plays a role in multiple signal transduction pathways in cells, such as DNA binding, phosphorylation, etc. Therefore, the potential for interaction with these signaling molecules is greater.

3. Cell proliferation and differentiation: EFCAB13 plays a role in cell cycle regulation, cell proliferation and differentiation, and therefore may be related to these processes.

4. Tumor formation: EFCAB13 is expressed in some tumors and may therefore be related to tumor formation.

5. Nerve signaling: EFCAB13 plays a role in the nervous system and therefore may be related to nerve signaling.

3. Future research prospects

EFCAB13, as a protein with complex structure and function, has attracted widespread research interest. In the future, researchers will continue to conduct research from the following aspects:

1. Drug screening: Using the drug target properties of EFCAB13, researchers will screen out compounds with potential therapeutic effects and provide new targets for subsequent drug development.

2. Bioinformatics analysis: Conduct in-depth research on the gene and protein structure of EFCAB13 to reveal its functional mechanisms in signal transduction, drug targets, etc.

3. Drug evaluation: Conduct biological activity and pharmacological evaluation of the screened compounds to provide a basis for further screening of drugs.

4. Clinical application: Based on the drug targets and drug screening results of EFCAB13, researchers will continue to develop drugs with therapeutic effects and contribute to human health.

in conclusion

As a protein with unique structure and function, EFCAB13 has broad application prospects in cell signaling and drug targets. Through in-depth study of the structure, function and drug target properties of EFCAB13, new ideas and methods can be provided for researchers in related fields, thus promoting the development of life sciences.

Protein Name: EF-hand Calcium Binding Domain 13

The "EFCAB13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EFCAB13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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