Target Name: LRBA
NCBI ID: G987
Review Report on LRBA Target / Biomarker Content of Review Report on LRBA Target / Biomarker
LRBA
Other Name(s): BGL | LRBA_HUMAN | LRBA variant 2 | Lipopolysaccharide-responsive and beige-like anchor protein | Beige-like protein | CDC4-like protein | vesicle trafficking, beach and anchor containing | Lipopolysaccharide-responsive and beige-like anchor protein (isoform 1) | CVID8 | LAB300 | Cell division cycle 4-like | CDC4L | LBA | Vesicle trafficking, beach and anchor containing | LRBA variant 1 | Lipopolysaccharide-responsive and beige-like anchor protein (isoform 2) | LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing | LPS responsive beige-like anchor protein, transcript variant 1 | LPS-responsive vesicle trafficking, beach and anchor containing | LPS responsive beige-like anchor protein | LPS responsive beige-like anchor protein, transcript variant 2

LRBA: A Potential Drug Target and Biomarker

LRBA (long non-coding RNA) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. LRBA is a key regulator of gene expression and has been shown to play a role in various cellular processes, including cell growth, differentiation, and inflammation.

The discovery of LRBA as a potential drug target comes as a promising development for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. LRBA has also been identified as a potential biomarker for monitoring disease progression and response to treatment.

Understanding the biology of LRBA

LRBA is a non-coding RNA molecule that is expressed in various tissues and cells throughout the body. It is highly expressed in the brain and has been shown to play a role in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

LRBA has been shown to regulate gene expression by binding to specific DNA sequences and modulating the activity of transcription factors. It has also been shown to play a role in the regulation of cellular processes, including cell growth, apoptosis, and inflammation.

In addition, LRBA has been shown to be involved in the regulation of cellular signaling pathways, including the TGF-β pathway. TGF-β is a well-established regulator of cell growth and has been implicated in the development and progression of various diseases, including cancer.

The potential drug target

The potential drug target for LRBA is based on its role in the regulation of cellular processes and its involvement in the TGF-β pathway. Drugs that target LRBA have the potential to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One approach to targeting LRBA is to use small molecules that modulate the activity of transcription factors, such as activators or inhibitors of TGF-β. These drugs have been shown to have therapeutic potential in the treatment of various diseases, including cancer and neurodegenerative diseases.

Another approach to targeting LRBA is to use antibodies that specifically recognize and target LRBA. These antibodies have the potential to selectively target LRBA in various tissues and cells and can be used to monitor the activity of LRBA in a controlled manner.

The potential biomarker

LRBA has also been identified as a potential biomarker for monitoring disease progression and response to treatment. Its expression has been shown to be affected by various diseases and therapeutic interventions, making it a potential indicator of disease severity and response to treatment.

For example, LRBA has been shown to be downregulated in various tissues and cells associated with neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This suggests that LRBA may be a potential biomarker for monitoring the progression of these diseases and response to therapeutic interventions.

Additionally, LRBA has been shown to be regulated by various diseases, including cancer. This suggests that LRBA may be a potential biomarker for monitoring the progression of cancer and response to therapeutic interventions.

Conclusion

LRBA is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. Its role in the regulation of cellular processes and its involvement in the TGF-β pathway make it a promising target for therapeutic interventions.

The potential drug targets for LRBA are based on its role in the regulation of cellular processes and its involvement in the TGF-β pathway. The potential biomarker for LRBA is its expression, which is regulated by various diseases and therapeutic interventions.

Future research is needed to fully understand the biology of LRBA and its potential as a drug target and biomarker. Further studies are needed to

Protein Name: LPS Responsive Beige-like Anchor Protein

Functions: Involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules (By similarity). Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria (PubMed:33773106)

The "LRBA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LRBA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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LRCH1 | LRCH2 | LRCH3 | LRCH4 | LRCOL1 | LRFN1 | LRFN2 | LRFN3 | LRFN4 | LRFN5 | LRG1 | LRGUK | LRIF1 | LRIG1 | LRIG2 | LRIG2-DT | LRIG3 | LRIG3-DT | LRIT1 | LRIT2 | LRIT3 | LRMDA | LRP1 | LRP10 | LRP11 | LRP12 | LRP1B | LRP2 | LRP2BP | LRP3 | LRP4 | LRP4-AS1 | LRP5 | LRP5L | LRP6 | LRP8 | LRPAP1 | LRPPRC | LRR1 | LRRC1 | LRRC10 | LRRC10B | LRRC14 | LRRC14B | LRRC15 | LRRC17 | LRRC18 | LRRC19 | LRRC2 | LRRC2-AS1 | LRRC20 | LRRC23 | LRRC24 | LRRC25 | LRRC26 | LRRC27 | LRRC28 | LRRC3 | LRRC30 | LRRC31 | LRRC32 | LRRC34 | LRRC36 | LRRC37A | LRRC37A11P | LRRC37A14P | LRRC37A15P | LRRC37A16P | LRRC37A17P | LRRC37A2 | LRRC37A3 | LRRC37A4P | LRRC37A5P | LRRC37A6P | LRRC37A7P | LRRC37A9P | LRRC37B | LRRC37BP1 | LRRC38 | LRRC39 | LRRC3B | LRRC3C | LRRC4 | LRRC40 | LRRC41 | LRRC42 | LRRC43 | LRRC45 | LRRC46 | LRRC47 | LRRC49 | LRRC4B | LRRC4C | LRRC52 | LRRC52-AS1 | LRRC53 | LRRC55 | LRRC56 | LRRC57 | LRRC58