LRRC38: A Promising Drug Target and Biomarker for Various Diseases

Target Name: LRRC38

NCBI ID: G126755

LRRC38

LRRC38: A Promising Drug Target and Biomarker for Various Diseases

LRRC38 (RP4-597A16.1) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the long non-coding RNA (lncRNA) family, which includes around 1,000 known lncRNAs. LRRC38 has been shown to play a role in various biological processes, including cell signaling, DNA replication, and gene regulation.

One of the most promising aspects of LRRC38 is its potential as a drug target. LRRC38 has been shown to interact with several protein kinases, including the brain-derived neurotrophic factor (BDNF) and the serine/threonine-protein kinase (STK-1). These interactions suggest that LRRC38 may be a useful target for drugs that target protein kinases, such as those used to treat depression, anxiety, and other psychiatric disorders.

Additionally, LRRC38 has been shown to be involved in the regulation of cellular processes that are important for brain development and function. For example, LRRC38 has been shown to play a role in the regulation of neuron migration and in the establishment of the spatial order of neural circuits in the brain.

LRRC38 is also of interest as a potential biomarker for various diseases, including cancer. For example, LRRC38 has been shown to be downregulated in various types of cancer, including breast, ovarian, and prostate cancer. This suggests that LRRC38 may be a useful biomarker for these diseases, and that targeting LRRC38 may be a promising strategy for cancer treatment.

Another potential application of LRRC38 is its role in the regulation of cellular processes that are important for wound healing and tissue regeneration. LRRC38 has been shown to play a role in the regulation of cell proliferation, migration, and the formation of tissues during wound healing. This suggests that LRRC38 may be a useful target for drugs that are used to promote wound healing and tissue regeneration.

In conclusion, LRRC38 is a protein that has been shown to play a role in various biological processes, including cell signaling, DNA replication, and gene regulation. Its potential as a drug target and biomarker make it an attractive target for further research and development. Further studies are needed to fully understand the role of LRRC38 in various biological processes and to determine its potential as a drug.

Protein Name: Leucine Rich Repeat Containing 38

Functions: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium

The "LRRC38 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LRRC38 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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