LOC100133177: A Drug Target / Disease Biomarker (G100133177)
LOC100133177: A Drug Target / Disease Biomarker
LOC100133177 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in high abundance in response to increased levels of thermal stress. HSPs play a crucial role in maintaining cellular homeostasis and have been implicated in a wide range of cellular processes, including stress response, DNA damage repair, and neurodegeneration.
LOC100133177 has been identified as a potential drug target for several reasons. Firstly, it is expressed in a variety of tissues and organs, which makes it an attractive target for therapeutic intervention. Secondly, its expression is often increased in response to stress, which suggests that targeting it may have therapeutic benefits in diseases that are characterized by increased cellular stress. Finally, LOC100133177 has been shown to play a role in several cellular processes that are implicated in a wide range of diseases, including neurodegenerative diseases, cancer, and cardiovascular disease.
One of the key challenges in studying LOC100133177 as a drug target is its expression pattern. LOC100133177 is expressed in a variety of tissues and organs, including the brain, heart, and kidneys, and its expression is often increased in response to stress. This makes it difficult to study its function in specific tissues and to determine how it contributes to cellular processes that are relevant to disease.
In order to study LOC100133177 as a drug target, researchers have used a variety of techniques to identify its functions. One approach is to use small interfering RNA (siRNA) to knockdown the expression of LOC100133177 in specific tissues and to assess the impact on cellular processes. Using this approach, researchers have found that LOC100133177 is involved in several cellular processes, including stress response, DNA damage repair, and neurotransmitter signaling.
Another approach is to use antibodies to study LOC100133177's distribution and localization in specific tissues. Using this approach, researchers have found that LOC100133177 is highly expressed in the brain and that it is primarily localized to the peri-synaptic region, which is the region between neurons where synaptic proteins are synthesized and modified.
In addition to these techniques, researchers have also used cell-based assays to study LOC100133177's function in specific cellular processes. For example, they have used live cell imaging techniques to assess the effects of LOC100133177 on cellular signaling processes, such as cell division and neurotransmitter release. Using these approaches, researchers have found that LOC100133177 plays a critical role in several cellular processes that are important for maintaining cellular homeostasis and that are implicated in a wide range of diseases.
Overall, LOC100133177 is an attractive drug target due to its diverse expression pattern and its involvement in several cellular processes that are important for maintaining cellular homeostasis. While further research is needed to fully understand its functions and to determine its potential as a drug target, the study of LOC100133177 is a promising direction for future research in this field.
Protein Name: Uncharacterized LOC100133177
More Common Targets
LOC100133284 | LOC100133331 | LOC100133920 | LOC100134317 | LOC100134368 | LOC100134391 | LOC100134868 | LOC100190986 | LOC100233156 | LOC100240728 | LOC100240734 | LOC100240735 | LOC100271840 | LOC100272216 | LOC100272217 | LOC100286922 | LOC100287036 | LOC100287290 | LOC100287329 | LOC100287413 | LOC100287792 | LOC100287834 | LOC100287846 | LOC100287944 | LOC100288069 | LOC100288162 | LOC100288208 | LOC100288637 | LOC100288656 | LOC100289230 | LOC100289283 | LOC100289308 | LOC100289333 | LOC100289361 | LOC100289470 | LOC100289473 | LOC100289495 | LOC100289511 | LOC100289561 | LOC100289580 | LOC100289656 | LOC100293211 | LOC100294145 | LOC100335030 | LOC100419773 | LOC100420587 | LOC100421561 | LOC100505498 | LOC100505502 | LOC100505585 | LOC100505664 | LOC100505715 | LOC100505716 | LOC100505841 | LOC100505912 | LOC100505915 | LOC100505978 | LOC100506023 | LOC100506071 | LOC100506076 | LOC100506124 | LOC100506207 | LOC100506236 | LOC100506274 | LOC100506281 | LOC100506379 | LOC100506403 | LOC100506422 | LOC100506444 | LOC100506446 | LOC100506472 | LOC100506474 | LOC100506499 | LOC100506514 | LOC100506532 | LOC100506606 | LOC100506634 | LOC100506639 | LOC100506667 | LOC100506730 | LOC100506974 | LOC100507002 | LOC100507006 | LOC100507053 | LOC100507054 | LOC100507156 | LOC100507165 | LOC100507221 | LOC100507250 | LOC100507336 | LOC100507346 | LOC100507351 | LOC100507389 | LOC100507412 | LOC100507424 | LOC100507443 | LOC100507513 | LOC100507520 | LOC100507547 | LOC100507577