Target Name: AATK
NCBI ID: G9625
Review Report on AATK Target / Biomarker Content of Review Report on AATK Target / Biomarker
AATK
Other Name(s): LMTK1 | LMR1 | AATYK | p35BP | apoptosis associated tyrosine kinase | lemur tyrosine kinase 1 | brain apoptosis-associated tyrosine kinase | Serine/threonine-protein kinase LMTK1 (isoform 1) | Serine/threonine-protein kinase LMTK1 | p35-binding protein | protein phosphatase 1, regulatory subunit 77 | AATYK1 | Apoptosis associated tyrosine kinase, transcript variant 1 | KIAA0641 | AATK variant 1 | PPP1R77 | CDK5-binding protein | Lemur tyrosine kinase 1 | Brain apoptosis-associated tyrosine kinase | Apoptosis-associated tyrosine kinase | LMTK1_HUMAN

AATK: Potential Drug Target Or Biomarker

AATK (Alkylator-Activated Transmembrane K channel) is a protein that is expressed in various tissues and cells throughout the body. It is a member of the family of channel proteins known as K channels and is involved in the regulation of ion channels. AATK is highly expressed in the brain and is also found in the heart, pancreas, and intestine.

AATK is involved in many different physiological processes in the body, including the regulation of neuronal excitability and the transmission of signals within the nervous system. It is also involved in the regulation of ion channels in the heart, which plays a critical role in the regulation of heart rate and blood pressure.

Recent studies have suggested that AATK may be a drug target or biomarker for a variety of neurological and psychiatric disorders, including epilepsy, schizophrenia, and depression. This is because AATK is known to be involved in the regulation of many different signaling pathways, and drugs that target AATK may have a wide range of potential therapeutic effects.

One of the potential benefits of targeting AATK is that it may be a safe drug to use, as it is highly expressed in many different tissues and cells and is not highly dependent on the concentration of the drug in the body. This may make it a useful target for drugs that are intended to be used safely and selectively.

In addition, AATK may be a good biomarker for tracking the effects of a drug on ion channels in the brain. This is because AATK is known to be involved in the regulation of many different ion channels, including those that are responsible for the rapid depolarization that occurs during an action potential. By measuring the levels of AATK in the brain after the drug has been administered, researchers can determine how the drug is affecting the levels of ion channels and the resulting changes in neural activity.

Another potential benefit of targeting AATK is that it may be a good target for drugs that are intended to modulate the activity of other ion channels. This is because AATK is known to be involved in the regulation of many different ion channels, and drugs that target AATK may have a wide range of potential therapeutic effects by modulating the activity of these channels.

In conclusion, AATK is a protein that is expressed in various tissues and cells throughout the body and is involved in the regulation of ion channels. It is suggested to be a potential drug target or biomarker for a variety of neurological and psychiatric disorders. Further research is needed to fully understand the role of AATK in the regulation of ion channels and its potential as a therapeutic target.

Protein Name: Apoptosis Associated Tyrosine Kinase

Functions: May be involved in neuronal differentiation

The "AATK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AATK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ABALON | ABAT | ABCA1 | ABCA10 | ABCA11P | ABCA12 | ABCA13 | ABCA17P | ABCA2 | ABCA3 | ABCA4 | ABCA5 | ABCA6 | ABCA7 | ABCA8 | ABCA9 | ABCB1 | ABCB10 | ABCB11 | ABCB4 | ABCB5 | ABCB6 | ABCB7 | ABCB8 | ABCB9 | ABCC1 | ABCC10 | ABCC11 | ABCC12 | ABCC13 | ABCC2 | ABCC3 | ABCC4 | ABCC5 | ABCC6 | ABCC6P1 | ABCC6P2 | ABCC8 | ABCC9 | ABCD1 | ABCD2 | ABCD3 | ABCD4 | ABCE1 | ABCF1 | ABCF1-DT | ABCF2 | ABCF3 | ABCG1 | ABCG2 | ABCG4 | ABCG5 | ABCG8 | ABHD1 | ABHD10 | ABHD11 | ABHD11-AS1 | ABHD12 | ABHD12B | ABHD13 | ABHD14A | ABHD14B | ABHD15 | ABHD16A | ABHD16B | ABHD17A | ABHD17AP1 | ABHD17AP4 | ABHD17AP5 | ABHD17AP6 | ABHD17B | ABHD17C | ABHD18 | ABHD2 | ABHD3 | ABHD4 | ABHD5 | ABHD6 | ABHD8 | ABI1 | ABI2 | ABI3 | ABI3BP | ABITRAM | ABL1 | ABL2 | ABLIM1 | ABLIM2 | ABLIM3 | ABO | ABR | ABRA | ABRACL | ABRAXAS1 | ABRAXAS2 | ABT1 | ABTB1 | ABTB2 | ABTB3 | ACAA1