Target Name: ZNF680
NCBI ID: G340252
Review Report on ZNF680 Target / Biomarker Content of Review Report on ZNF680 Target / Biomarker
ZNF680
Other Name(s): zinc finger protein 680 | Zinc finger protein 680 | Zinc finger protein 680 (isoform 1) | ZNF680 variant 1 | Zinc finger protein 680, transcript variant 1 | ZN680_HUMAN

ZNF680: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes, including gene regulation, DNA replication, and cell signaling. ZNF680, a specific ZFP, has been identified as a potential drug target and biomarker. In this article, we will explore the biology of ZNF680, its potential drug targeting, and its potential as a biomarker for various diseases.

Biochemistry and Function

ZNF680 is a 21-kDa protein that consists of 680 amino acid residues. It is expressed in various tissues, including brain, heart, skeletal muscles, and organs. ZNF680 is a zinc finger protein that displays a characteristic ZNF-like domain, composed of a conserved core of 12 amino acids, followed by a variable region that includes a ZNF681 domain and a C-terminal hypervariable region (HVR).

The ZNF681 domain is a conserved region that is present in various zinc finger proteins, including ZNF680. It is known to play a crucial role in the regulation of gene expression and DNA replication. The C-terminal HVR is highly conserved and has been implicated in various cellular processes, including cell signaling, DNA replication, and gene regulation.

Potential Drug Target

ZNF680 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the key reasons for its potential drug targeting is its involvement in cell signaling. ZNF680 is a component of the S/T-complex, a protein complex that is involved in the regulation of cell signaling pathways, including T cell signaling.

The S/T-complex is a protein complex that consists of various proteins, including ZNF680, that work together to regulate the activity of the T-cell receptor (TCR). The S/T-complex plays a crucial role in the regulation of cell signaling pathways, including the development and activation of T cells, B cells, and natural killer cells.

In addition to its involvement in cell signaling, ZNF680 has also been shown to play a role in the regulation of DNA replication. ZNF680 has been shown to be involved in the regulation of DNA replication in various cell types, including cancer cells.

Potential Biomarker

ZNF680 has also been identified as a potential biomarker for various diseases due to its unique structure and its involvement in various cellular processes. One of the key reasons for its potential as a biomarker is its expression pattern in various tissues and its ability to be used as a protein biomarker.

ZNF680 is expressed in various tissues, including brain, heart, skeletal muscles, and organs, and its expression patterns have been shown to be regulated by various factors, including gene expression, DNA replication, and cellular signaling pathways. This suggests that ZNF680 could be used as a protein biomarker for various diseases, including cancer, cardiovascular disease, and neurological disorders.

Conclusion

ZNF680 is a unique protein that has been identified as a potential drug target and biomarker. Its structure and function have been studied extensively, and its potential as a drug target and biomarker continue to be explored. ZNF680 is involved in the regulation of cell signaling pathways and DNA replication, making it a promising target for drug development. Its potential as a biomarker for various diseases also makes it an attractive candidate for future research.

Protein Name: Zinc Finger Protein 680

Functions: May be involved in transcriptional regulation

The "ZNF680 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF680 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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