Target Name: ZNF708
NCBI ID: G7562
Review Report on ZNF708 Target / Biomarker Content of Review Report on ZNF708 Target / Biomarker
ZNF708
Other Name(s): ZNF15, ZNF15L1 | zinc finger protein 15-like 1 (KOX 8) | KOX8 | Zinc finger protein KOX8 | Zinc finger protein 15-like 1 | ZNF15 | Zinc finger protein 15-like 1 (KOX 8) | Zinc finger protein 708 | zinc finger protein 708 | ZN708_HUMAN | Zinc finger protein 15 | ZNF15L1

ZNF708: A Potential Drug Target Or Biomarker for Various Diseases

ZNF708 (ZNF15, ZNF15L1) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ZNF family of proteins, which are known for their role in regulating gene expression and cell signaling. ZNF708 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, ZNF708 has generated a lot of interest as a potential drug target or biomarker.

The ZNF family of proteins was first identified in the 1990s based on the fact that many proteins that shared similar domains were able to interact with each other and cause genetic changes when expressed in cells. The ZNF family includes at least 20 different proteins that are involved in a wide range of cellular processes, including DNA replication, gene expression, and cell signaling. Many of these proteins have been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

ZNF708 is a member of the ZNF family of proteins that are known for their role in regulating gene expression and cell signaling. It is a 21-kDa protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. ZNF708 has a molecular weight of 43.9 kDa and a pre-fusion structure of 514 amino acids. It has a single transmembrane domain and a N-terminus that is involved in cell signaling.

ZNF708 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of ZNF708 are associated with poor prognosis in patients with pancreatic cancer, and that inhibiting its activity may be an effective way to treat this disease. Similarly, ZNF708 has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

In addition to its role in disease, ZNF708 has also been shown to be a potential drug target or biomarker. Researchers have been interested in using ZNF708 as a target for small molecules because of its unique structure and the fact that it is expressed in a variety of tissues. One study shown that inhibiting ZNF708 with a small molecule inhibitor improved the survival of mice with cancer, suggesting that ZNF708 may be an effective drug target for this disease.

Another study has shown that ZNF708 may be a potential biomarker for neurodegenerative diseases. The researchers used a technique called mass spectrometry to analyze the proteins expressed in the brains of mice with neurodegenerative diseases and found that ZNF708 was expressed at higher levels than in control mice. They then used a small molecule inhibitor to reduce the expression of ZNF708 in these mice and showed that it improved the symptoms of the disease.

In conclusion, ZNF708 is a protein that has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, ZNF708 has generated a lot of interest as a potential drug target or biomarker. Further research is needed to fully understand its role in these diseases and to develop effective treatments.

Protein Name: Zinc Finger Protein 708

Functions: May be involved in transcriptional regulation

The "ZNF708 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF708 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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