TATDN3: A Potential Drug Target and Biomarker (G128387)

Target Name: TATDN3

NCBI ID: G128387

TATDN3

TATDN3: A Potential Drug Target and Biomarker

Introduction

Tumor suppressor genes (TSGs) are important regulators of cancer growth and progression. Many TSGs have been identified, but few have been well characterized. The protein TATDN3 is one of the TSGs that has garnered significant interest due to its unique structure and biology. TATDN3 is a nuclear protein that is expressed in a variety of tissues and cells, including epithelial, hematopoietic, and nervous system cells. It is characterized by a unique N-terminal domain that consists of a nucleotide-binding oligomerization domain (NBO), a conserved N-terminal region, and a C-terminal TAT-like domain.

The NBO domain is responsible for TATDN3's nuclear localization and plays a critical role in its functions. The N-terminal region is rich in putative active sites that are involved in various cellular processes, including DNA binding, RNA binding, and protein-protein interactions. The C-terminal TAT-like domain is known for its conserved cysteine 鈥嬧?媟esidues, which is involved in protein-protein interactions and may contribute to TATDN3's stability.

TATDN3 is a key regulator of the DNA double helix, and its functions in cell biology are essential for understanding the mechanisms of cancer progression. One of the key functions of TATDN3 is its role in DNA repair. TATDN3 is a DNA-protein complex that is involved in the repair of DNA double-strand breaks, including those caused by endogenous and exogenous factors. Studies have shown that TATDN3 plays a critical role in the regulation of DNA repair efficiency, and that its expression is often associated with poor DNA repair outcomes in cancer cells.

In addition to its role in DNA repair, TATDN3 is also involved in the regulation of cell growth and differentiation. It has also been shown to play a critical role in the regulation of cell proliferation and the maintenance of stem cell properties. to be involved in the regulation of cell survival, as it has been shown to play a role in the regulation of apoptosis.

TATDN3 is also involved in the regulation of cellular signaling pathways. It has been shown to play a critical role in the regulation of cell signaling pathways, including the TGF-β pathway. TATDN3 has been shown to interact with the transcription factor TGF-β1, and to play a role in the regulation of TGF-β1-mediated signaling pathways.

Despite its significant impact on cellular biology, TATDN3 is not well understood. The functions of TATDN3 are not well understood, and there is a need for further research to determine its role in cancer progression. One potential avenue for research is the targeting of TATDN3 as a drug target.

The Protein TATDN3

TATDN3 is a 21 kDa protein that is expressed in a variety of tissues and cells, including epithelial, hematopoietic, and nervous system cells. It is characterized by a unique N-terminal domain that consists of a nucleotide-binding oligomerization domain (NBO), a conserved N-terminal region, and a C-terminal TAT-like domain.

The NBO domain is responsible for TATDN3's nuclear localization and plays a critical role in its functions. The N-terminal region is rich in putative active sites that are involved in various cellular processes, including DNA binding, RNA binding, and protein-protein interactions. The C-terminal TAT-like domain is known for its conserved cysteine 鈥嬧?媟esidues, which are involved in protein-protein interactions and may contribute to TATDN3's stability.

TATDN3 is a key regulator of the DNA double helix, and its functions in cell biology are essential for understanding the mechanisms of cancer progression. One of the key functions of TATDN3 is its role in DNA repair. TATDN3 is a DNA-protein complex that is involved in the repair of DNA double-strand breaks, including those caused by endogenous and exogenous factors. Studies have shown that TATDN3 plays a critical role in the regulation of DNA repair efficiency, and that its expression is often associated with poor DNA repair outcomes in cancer cells.

In addition to its role in DNA repair, TATDN3 is also involved in the regulation of cell growth and differentiation. It has been shown to play

Protein Name: TatD DNase Domain Containing 3

Functions: Putative deoxyribonuclease

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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