Unlocking the Potential of COPS7A: A Promising Drug Target and Biomarker

Target Name: COPS7A

NCBI ID: G50813

COPS7A

Unlocking the Potential of COPS7A: A Promising Drug Target and Biomarker

COPS7A (dermal papilla-derived protein 10) is a protein that has garnered significant attention in the scientific community due to its unique structure and biological function. As a protein expressed in human skin papillae, it has been shown to play a critical role in skin development and maintenance. While the exact function of COPS7A is still being explored, research has uncovered several promising implications for its potential as a drug target or biomarker. In this article, we will delve into the research on COPS7A, exploring its potential as a drug target and biomarker, as well as its potential clinical applications.

Potential Drug Target

COPS7A has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. The protein is composed of 218 amino acid residues and has a calculated molecular weight of 24 kDa. It is expressed in the skin, hair, and nails, and has been shown to play a critical role in the development and maintenance of these tissues.

One of the key features of COPS7A is its ability to interact with various signaling pathways, including TGF-β and NF-kappa-B. These signaling pathways are involved in the regulation of cellular processes such as cell growth, differentiation, and inflammation. By modulating these signaling pathways, COPS7A has been shown to contribute to the development and maintenance of various skin diseases, including cancer, wound healing, and skin infection.

In addition to its involvement in signaling pathways, COPS7A has also been shown to play a critical role in the regulation of cellular processes that are critical for skin health, such as cell death and cell proliferation. Its expression has been shown to be associated with the survival and proliferation of skin cells, and has been shown to play a role in the regulation of cell death in response to various stimuli, including UV radiation and chemotherapy.

Potential Biomarker

COPS7A has also been identified as a potential biomarker for various skin diseases, including cancer, wound healing, and skin infection. Its expression has been shown to be associated with the development and progression of these diseases, and has been shown to play a role in the regulation of cellular processes that are critical for their development.

One of the key advantages of COPS7A as a biomarker is its stability and its ability to be detected in various types of skin samples, including formalin-fixed and paraffin- embedded samples. This makes it a promising tool for the detection and diagnosis of skin diseases, including cancer.

In addition to its potential as a drug target and biomarker, COPS7A has also been shown to have potential clinical applications. Studies have shown that inhibiting the activity of COPS7A has the potential to treat various skin diseases, including cancer, wound healing, and skin infection.

Conclusion

In conclusion, COPS7A is a protein that has significant potential as a drug target and biomarker. Its unique structure and its involvement in various cellular processes make it an attractive target for the development of new therapies for skin diseases. As research continues to uncover the functions of COPS7A, its potential clinical applications are likely to expand.

Protein Name: COP9 Signalosome Subunit 7A

Functions: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively

The "COPS7A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about COPS7A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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