Target Name: COPA
NCBI ID: G1314
Review Report on COPA Target / Biomarker Content of Review Report on COPA Target / Biomarker
COPA
Other Name(s): alpha coat protein | alpha-Coat protein | alpha Coat protein | COPA_HUMAN | coatomer protein complex subunit alpha | proxenin | Coatomer subunit alpha (isoform 1) | xenin | COPA variant 2 | coatomer protein complex, subunit alpha | Xenin | COPA variant 1 | Xenopsin-related peptide | Alpha-COP | Coatomer subunit alpha | Coatomer subunit alpha (isoform 2) | Proxenin | FLJ26320 | HEP-COP | Alpha-coat protein | COPI coat complex subunit alpha | HEPCOP | COPI coat complex subunit alpha, transcript variant 2 | COPI coat complex subunit alpha, transcript variant 1 | AILJK | alpha-coat protein | alpha-COP

COPA: A Potential Drug Target and Biomarker for Alpha Coat Protein

Alpha coat protein (COPA) is a protein that is expressed in many tissues and cells in the human body. It is involved in various physiological processes, including cell signaling, migration, and invasion. COPA has also been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, COPA has become an attractive target for drug development. In this article, we will explore the biology of COPA and its potential as a drug target and biomarker.

The Biology of COPA

COPA is a type-I transmembrane protein that is expressed in many tissues and cells in the human body. It is composed of four domains: an extracellular domain, a transmembrane domain, an intracellular domain, and a nuclear domain. The extracellular domain is responsible for the protein's ability to interact with various cell signaling pathways. The transmembrane domain is responsible for the protein's ability to span the cell membrane and interact with various intracellular signaling pathways. The intracellular domain is responsible for the protein's ability to interact with various intracellular signaling pathways and targets. The nuclear domain is responsible for the protein's ability to interact with various nuclear signaling pathways.

COPA has been shown to be involved in a number of physiological processes. For example, it is involved in cell signaling, including the regulation of cell proliferation, differentiation, and survival. It is also involved in the regulation of cell migration and invasion, as well as in the regulation of various signaling pathways, including TGF-β, FGF, and Wnt.

In addition to its involvement in various physiological processes, COPA has also been shown to be involved in the development and progression of a number of diseases. For example, it has been implicated in the development of cancer, including breast cancer, ovarian cancer, and prostate cancer. It has also been implicated in the development of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It has also been implicated in the development of autoimmune disorders, including rheumatoid arthritis, lupus, and multiple sclerosis.

Potential as a Drug Target

The potential of COPA as a drug target is due to its involvement in various physiological processes and its involvement in the development and progression of a number of diseases.

One potential mechanism by which COPA could be targeted as a drug is its role in cell signaling. COPA has been shown to play a role in the regulation of cell signaling, including the regulation of cell proliferation, differentiation, and survival. As a result, drugs that target COPA's signaling pathways could be effective in treating a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Another potential mechanism by which COPA could be targeted as a drug is its role in the regulation of cell migration and invasion. COPA has been shown to play a role in the regulation of cell migration and invasion, as well as in the regulation of various signaling pathways, including TGF-β, FGF, and Wnt. As a result, drugs that target COPA's migration and invasion pathways could be effective in treating a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In addition to its role in cell signaling and migration, COPA is also involved in the regulation of various intracellular signaling pathways. As a result, drugs that target COPA's intracellular signaling pathways could be effective in treating a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Potential as a Biomarker

The potential of COPA as a biomarker is due to its involvement in various physiological processes and its involvement in the development and progression of a number of diseases.

One potential use for COPA as a biomarker is its ability to be targeted by drugs. Because COPA is involved in various physiological processes and is involved in the development and progression of a number of diseases, drugs that target its signaling pathways could be effective in treating a number of diseases. In addition, because COPA is a type-I transmembrane protein, it is relatively stable in cells and can be used as a reliable biomarker for the expression of certain genes.

Another potential use for

Protein Name: COPI Coat Complex Subunit Alpha

Functions: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity)

The "COPA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about COPA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

COPB1 | COPB2 | COPB2-DT | COPE | COPG1 | COPG2 | COPG2IT1 | COPRS | COPS2 | COPS3 | COPS4 | COPS5 | COPS6 | COPS7A | COPS7B | COPS8 | COPS8P3 | COPS9 | COPZ1 | COPZ2 | COQ10A | COQ10B | COQ2 | COQ3 | COQ4 | COQ5 | COQ6 | COQ7 | COQ8A | COQ8B | COQ9 | CORIN | CORO1A | CORO1B | CORO1C | CORO2A | CORO2B | CORO6 | CORO7 | CORT | Corticotropin-Releasing Factor (CRF) Receptor | COTL1 | COTL1P1 | COX1 | COX10 | COX10-DT | COX11 | COX14 | COX15 | COX16 | COX17 | COX18 | COX19 | COX2 | COX20 | COX3 | COX4I1 | COX4I1P1 | COX4I2 | COX5A | COX5B | COX6A1 | COX6A2 | COX6B1 | COX6B1P2 | COX6B1P3 | COX6B1P5 | COX6B1P7 | COX6B2 | COX6C | COX6CP1 | COX6CP17 | COX7A1 | COX7A2 | COX7A2L | COX7A2P2 | COX7B | COX7B2 | COX7C | COX7CP1 | COX8A | COX8BP | COX8C | CP | CPA1 | CPA2 | CPA3 | CPA4 | CPA5 | CPA6 | CPAMD8 | CPB1 | CPB2 | CPB2-AS1 | CPD | CPE | CPEB1 | CPEB1-AS1 | CPEB2 | CPEB2-DT