Target Name: CRYZ
NCBI ID: G1429
Review Report on CRYZ Target / Biomarker Content of Review Report on CRYZ Target / Biomarker
CRYZ
Other Name(s): Crystallin, zeta | epididymis secretory sperm binding protein | CRYZ variant 1 | NADPH2:quinone reductase | DKFZp779E0834 | Zeta-crystallin | Quinone oxidoreductase | Crystallin zeta, transcript variant 1 | Quinone oxidoreductase (isoform a) | NADPH:quinone reductase (isoform a) | OTTHUMP00000011211 | crystallin zeta | OTTHUMP00000011212 | Zeta crystallin | FLJ41475 | crystallin, zeta (quinone reductase) | QOR_HUMAN | NADPH:quinone reductase

Unlocking The Secrets of CRYZ: Understanding The Protein's Role in The Retina

CRYZ (Crystallin, zeta) is a protein that is expressed in the brain and is known for its role in the structure and function of the retina. It is composed of two subunits, alpha-crystallin (伪-Cry) and beta-crystallin (尾-Cry), that are held together by a disulfide bond.

The 伪-Cry subunit is the most abundant protein in the retina and is responsible for the structural integrity of the retina. It is involved in the formation of the retina's blood vessels and is also involved in the production of the photoreceptors that transmit visual information to the brain.

The 尾-Cry subunit is also an important protein in the retina and is involved in the structure and function of the retina's photoreceptors. It helps to maintain the stability of the photoreceptor axons and is also involved in the production of the neurotransmitter serotonin.

In addition to its role in the retina, CRYZ is also expressed in other tissues and is involved in a variety of physiological processes. It is involved in the regulation of cell signaling, cell adhesion, and cell migration. It is also involved in the production of various signaling molecules, including Wnt, which plays a role in the development and maintenance of tissues.

Despite its importance in many physiological processes, CRYZ is not well understood. little is known about its structure and function, and it is not clear how it contributes to the normal functioning of the retina.

However, the study of CRYZ has potential implications for the development of new treatments for a variety of disorders, including neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Because CRYZ is involved in the formation of the retina and the regulation of cell signaling, it may be a useful target for drugs that can promote the growth and survival of retinal cells, or that can inhibit the activity of molecules that damage the retina.

Additionally, the study of CRYZ may also have implications for the understanding of the aging process. As we age, the number and function of retinal cells decline, leading to the development of age-related macular degeneration (AMD). The study of CRYZ may reveal new insights into the role of this protein in the aging process and the development of AMD.

In conclusion, CRYZ is a protein that is expressed in the brain and is involved in the structure and function of the retina. Despite its importance, little is known about its structure and function. Further study is needed to understand its potential role in the development and treatment of various disorders, including neurodegenerative diseases and aging.

Protein Name: Crystallin Zeta

Functions: Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding

The "CRYZ Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CRYZ comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CRYZL1 | CRYZL2P | CRYZL2P-SEC16B | CS | CSAD | CSAG1 | CSAG2 | CSAG3 | CSAG4 | CSDC2 | CSDE1 | CSE1L | CSF1 | CSF1R | CSF2 | CSF2RA | CSF2RB | CSF2RBP1 | CSF3 | CSF3R | CSGALNACT1 | CSGALNACT2 | CSH1 | CSH2 | CSHL1 | CSK | CSKMT | CSMD1 | CSMD2 | CSMD2-AS1 | CSMD3 | CSN1S1 | CSN1S2AP | CSN1S2BP | CSN2 | CSN3 | CSNK1A1 | CSNK1A1L | CSNK1A1P1 | CSNK1D | CSNK1E | CSNK1G1 | CSNK1G2 | CSNK1G2-AS1 | CSNK1G3 | CSNK2A1 | CSNK2A2 | CSNK2A3 | CSNK2B | CSPG4 | CSPG4P10 | CSPG4P11 | CSPG4P12 | CSPG4P13 | CSPG4P1Y | CSPG4P2Y | CSPG4P3Y | CSPG5 | CSPP1 | CSRNP1 | CSRNP2 | CSRNP3 | CSRP1 | CSRP2 | CSRP3 | CSRP3-AS1 | CST Complex | CST1 | CST11 | CST13P | CST2 | CST3 | CST4 | CST5 | CST6 | CST7 | CST8 | CST9 | CST9L | CST9LP1 | CSTA | CSTB | CSTF1 | CSTF2 | CSTF2T | CSTF3 | CSTL1 | CSTPP1 | CT45A1 | CT45A10 | CT45A2 | CT45A3 | CT45A5 | CT45A6 | CT45A9 | CT47A1 | CT47A10 | CT47A11 | CT47A12 | CT47A2