Target Name: ADPRH
NCBI ID: G141
Review Report on ADPRH Target / Biomarker Content of Review Report on ADPRH Target / Biomarker
ADPRH
Other Name(s): ADP-ribosylhydrolase ARH1 | [Protein ADP-ribosylarginine] hydrolase | ADP-ribosylarginine hydrolase, transcript variant 1 | ARH1 | ADP-ribosylhydrolase ARH1 (isoform 1) | ADPRH_HUMAN | ADPRH variant 1 | hARH1 | ADP-ribosylarginine hydrolase | ADP-ribose-L-arginine cleaving enzyme

ADPRH: A Potential Drug Target and Biomarker

ADP-ribosylhydrolase (ADPRH) is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the repair and maintenance of RNA stability, and is highly conserved across different species. ADPRH is also known as ARH1, and is a potential drug target and biomarker.

ADPRH is a protein that is composed of 256 amino acids. It has a molecular weight of 31 kDa, and a pre-steady state activity of 13.9 kDa. ADPRH is highly conserved across different species, and is found in various organisms, including bacteria, archaea, and eukaryotes.

ADPRH is involved in the repair and maintenance of RNA stability. RNA is a critical molecule in the cell, and is responsible for carrying genetic information from the DNA to the ribosome, where it is translated into proteins. ADPRH is involved in the post-transcriptional modification of RNA, which is a critical step in the regulation of gene expression.

ADPRH is also involved in the degradation of damaged RNA. Damaged RNA can no longer be translated into proteins, and can be either degraded or translated into a functional RNA. ADPRH is involved in the degradation of damaged RNA by the ubiquitin-proteasome system.

ADPRH is a potential drug target because of its role in the regulation of RNA stability. By targeting ADPRH, researchers may be able to manipulate RNA stability and improve the translation of RNA into proteins. This could lead to a variety of therapeutic benefits, including the treatment of diseases such as cancer, where the regulation of RNA stability is disrupted.

ADPRH is also a potential biomarker for certain diseases. The expression of ADPRH has been detected in a variety of tissues and conditions, including cancer, neurodegenerative diseases, and RNA-related diseases. By measuring the expression of ADPRH, researchers may be able to diagnose and monitor the progression of these diseases.

In conclusion, ADP-ribosylhydrolase (ADPRH) is a protein that is involved in the repair and maintenance of RNA stability. It is a potential drug target and biomarker, and its study may have a variety of therapeutic and diagnostic implications. Further research is needed to fully understand the role of ADPRH in the regulation of RNA stability and its potential as a drug target and biomarker.

Protein Name: ADP-ribosylarginine Hydrolase

Functions: Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins

The "ADPRH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ADPRH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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