DHX8: A Potential Drug Target and Biomarker (G1659)

Target Name: DHX8

NCBI ID: G1659

DHX8

DHX8: A Potential Drug Target and Biomarker

Dihu DHX8 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the heat shock protein (HSP) family and has been shown to play a role in various physiological processes in the body. One of the interesting aspects of DHX8 is its potential as a drug target and biomarker.

The discovery of DHX8 as a drug target comes from a study by the researchers at the University of California, San Diego. The study showed that DHX8 was expressed in the brains of individuals with Alzheimer's disease and that it was associated with the development of neurofibrillary tangles and beta-amyloid plaques, two of the hallmark hallmarks of Alzheimer's disease. The researchers also found that inhibiting DHX8 reduced the formation of neurofibrillary tangles and beta-amyloid plaques in animal models of Alzheimer's disease.

This finding suggests that DHX8 may be a potential drug target for Alzheimer's disease. If DHX8 can be effectively inhibited, it may be possible to slow down or even reverse the progression of Alzheimer's disease. This could have a significant impact on the treatment of the disease and could lead to a more effective treatment option for patients.

In addition to its potential as a drug target, DHX8 has also been shown to be a potential biomarker for Alzheimer's disease. The researchers at the University of California, San Diego used a technique called RNA-based assay to measure the expression of DHX8 in the brains of individuals with Alzheimer's disease. They found that DHX8 was expressed in the brains of individuals with Alzheimer's disease and that its expression was associated with the severity of the disease.

This finding suggests that DHX8 may be a useful biomarker for the diagnosis and monitoring of Alzheimer's disease. If DHX8 can be used as a biomarker for the disease, it may be possible to develop a diagnostic test that could be used to diagnose Alzheimer's disease at an early stage, when the disease is most treatable.

In conclusion, DHX8 is a protein that has been shown to play a role in various physiological processes in the body. The potential drug target and biomarker properties of DHX8 make it an attractive target for research in the field of Alzheimer's disease. Further studies are needed to fully understand its potential as a drug and biomarker.

Protein Name: DEAH-box Helicase 8

Functions: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (PubMed:8608946)

The "DHX8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DHX8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets