Target Name: DIO2
NCBI ID: G1734
Review Report on DIO2 Target / Biomarker Content of Review Report on DIO2 Target / Biomarker
DIO2
Other Name(s): iodothyronine deiodinase 2 | type 2 DI | Type-II 5'-deiodinase | type-II 5'-deiodinase | deiodonase-2 | SelY | DIO2 variant 1 | IOD2_HUMAN | Iodothyronine deiodinase 2, transcript variant 1 | Thyroxin

DIO2: A Potential Drug Target and Biomarker

Dio2 (2,3-dihydroxy-6,7-dimethoxy-2,1,3,5-tetrahydroxybenzene) is a naturally occurring compound that has been found to have various health benefits, including anti-inflammatory and antioxidant effects. The potential drug target and biomarker properties of Dio2 have made it an attractive target for scientific research and development. In this article, we will explore the potential drug target and biomarker properties of Dio2.

Dio2 as a Drug Target

Dio2 has been shown to interact with various cellular components and molecules, including actinin, a protein that plays a critical role in cell signaling. actinin is a protein that is known to be involved in cell signaling, including the regulation of cell growth, differentiation, and survival.

Studies have shown that Dio2 can inhibit the activity of the protein actinin, leading to the inhibition of cell signaling. This inhibition of actinin activity can lead to the inhibition of cell growth and the inhibition of the development of cancer.

In addition to its interaction with actinin, Dio2 has also been shown to interact with other proteins, including tyrosine kinase, a protein that is involved in cell signaling. This interaction between Dio2 and tyrosine kinase can lead to the inhibition of tyrosine kinase activity, which can lead to the inhibition of cell signaling.

Dio2 as a Biomarker

Dio2 has been shown to have various antioxidant properties, including the ability to neutralize free radicals and the ability to reduce inflammation. These properties make Dio2 an attractive biomarker for the development of cancer.

Studies have shown that Dio2 has the ability to inhibit the production of reactive oxygen species (ROS), which are free radicals that can cause damage to cellular components and contribute to the development of cancer. In addition, Dio2 has also been shown to have the ability to reduce inflammation, which can also contribute to the development of cancer.

Dio2 has also been shown to have the ability to stimulate the production of antioxidants, such as superoxide dismutase (SOD), which can help to neutralize free radicals and reduce inflammation.

Conclusion

In conclusion, Dio2 has the potential to be a drug target and biomarker. Its interaction with actinin and tyrosine kinase, as well as its antioxidant and anti-inflammatory properties, make it an attractive target for scientific research and development. Further studies are needed to fully understand the potential drug target and biomarker properties of Dio2.

Protein Name: Iodothyronine Deiodinase 2

Functions: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development

The "DIO2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DIO2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DIO2-AS1 | DIO3 | DIO3OS | DIP2A | DIP2A-IT1 | DIP2B | DIP2C | DIP2C-AS1 | Dipeptidase | Dipeptidyl-Peptidase | DIPK1A | DIPK1B | DIPK1C | DIPK2A | DIPK2B | DIRAS1 | DIRAS2 | DIRAS3 | DIRC1 | DIRC3 | DIRC3-AS1 | DIS3 | DIS3L | DIS3L2 | DISC1 | DISC1FP1 | DISC2 | Disintegrin and Metalloproteinase domain-containing protein (ADAM) (nospecified subtype) | DISP1 | DISP2 | DISP3 | DIXDC1 | DKC1 | DKFZp434L192 | DKFZp451A211 | DKFZp451B082 | DKFZP586I1420 | DKK1 | DKK2 | DKK3 | DKK4 | DKKL1 | DLAT | DLC1 | DLD | DLEC1 | DLEU1 | DLEU2 | DLEU2L | DLEU7 | DLEU7-AS1 | DLG1 | DLG1-AS1 | DLG2 | DLG3 | DLG3-AS1 | DLG4 | DLG5 | DLG5-AS1 | DLGAP1 | DLGAP1-AS1 | DLGAP1-AS2 | DLGAP1-AS5 | DLGAP2 | DLGAP3 | DLGAP4 | DLGAP5 | DLK1 | DLK2 | DLL1 | DLL3 | DLL4 | DLST | DLSTP1 | DLX1 | DLX2 | DLX2-DT | DLX3 | DLX4 | DLX5 | DLX6 | DLX6-AS1 | DM1-AS | DMAC1 | DMAC2 | DMAC2L | DMAP1 | DMBT1 | DMBT1L1 | DMBX1 | DMC1 | DMD | DMGDH | DMKN | DMP1 | DMPK | DMRT1 | DMRT2 | DMRT3 | DMRTA1