Target Name: DIDO1
NCBI ID: G11083
Review Report on DIDO1 Target / Biomarker Content of Review Report on DIDO1 Target / Biomarker
DIDO1
Other Name(s): DIDO1 variant 5 | DIO1 | DIDO | C20orf158 | DATF-1 | DIDO3 | Death-inducer obliterator 1 (isoform c) | Death-inducer obliterator 1 | Death inducer-obliterator 1, transcript variant 5 | BYE1 | DIDO1_HUMAN | death inducer-obliterator 1 | DATF1 | hDido1 | Death-inducer obliterator 1 (isoform a) | Death inducer-obliterator 1, transcript variant 1 | DIO-1 | dJ885L7.8 | Death-associated transcription factor 1 | DIDO2 | death-associated transcription factor 1 | DIDO1 variant 1

DIDO1 Variant 5: A Potential Drug Target and Biomarker for Neurodegenerative Disorders

Dido1 (DIDO1 variant 5) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell death and has been implicated in a number of diseases, including neurodegenerative disorders, cancer, and autoimmune diseases.

The original DIDO1 gene has four exons, but there are several variants of the gene that have different numbers of exons. DIDO1 variant 5 is one of these variants and has one additional exon compared to the original form.

DIDO1 variant 5 is a splice variant and has been identified in a variety of organisms, including humans, animals, and bacteria. It is expressed in a range of tissues, including the brain, heart, and kidneys, and has been shown to play a role in a number of important biological processes, including cell death, inflammation, and fibrosis.

DIDO1 variant 5 has also been shown to be involved in a number of diseases and disorders, including neurodegenerative disorders, cancer, and autoimmune diseases. It is thought to be a potential drug target and may be a useful biomarker for the diagnosis and treatment of these diseases.

The Protein Structure and Function

DIDO1 variant 5 is a 21-kDa protein that is expressed in the brain and other tissues of the body. It is composed of 198 amino acid residues and has a calculated pI of 4.8.

The protein has a number of unique features that are distinct from the original DIDO1 gene. One of the most notable is its ability to form a homotimeric complex with itself, a process that is thought to be important for the regulation of cell death.

In addition, DIDO1 variant 5 has been shown to have a number of different functions in various tissues. For example, it has been shown to be involved in the regulation of cell death in the brain and has been shown to play a role in the development of neurodegenerative disorders.

DIDO1 variant 5 has also been shown to be involved in the regulation of inflammation and fibrosis in various tissues. For example, it has been shown to be involved in the regulation of the production of pro-inflammatory cytokines in response to tissue damage.

DIDO1 variant 5 has also been shown to have a number of different interactions with other proteins in the body. For example, it has been shown to interact with the protein Bcl-2 and has been shown to be regulated by the protein PDGF-BB.

DIDO1 variant 5 is a versatile protein that has a number of different functions in the body. Its unique structure and function make it an attractive candidate for further study and potential drug development.

The Potential Applications of DIDO1 variant 5

DIDO1 variant 5 is a protein that has a number of potential applications as a drug target or biomarker. Its ability to form a homotimeric complex with itself and its unique structure and function make it an attractive candidate for the development of new therapies for a variety of diseases.

One potential application of DIDO1 variant 5 is in the treatment of neurodegenerative disorders. The regulation of cell death and inflammation by DIDO1 variant 5 is thought to play a role in the development of these disorders, and targeting this protein may be a potential strategy for the development of new treatments.

DIDO1 variant 5 may also be a useful biomarker for the diagnosis and treatment of cancer. Its regulation of cell death and inflammation by DIDO1 variant 5 may be a potential target for cancer therapies and could be used as a marker for the diagnosis and prognosis of cancer.

In addition, DIDO1 variant 5 may be a useful target for the development of new therapies for autoimmune diseases. Its regulation of cell death and inflammation by DIDO1 variant 5 is

Protein Name: Death Inducer-obliterator 1

Functions: Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development

The "DIDO1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DIDO1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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