A closer look at F3 (TF_HUMAN), a drug target and biomarker for the treatment of human diseases

Target Name: F3

NCBI ID: G2152

Content of Review Report on F3 Target / Biomarker

A closer look at F3 (TF_HUMAN), a drug target and biomarker for the treatment of human diseases

F3 (TF_HUMAN) is a protein that has been identified as a potential drug target and biomarker for the treatment of various human diseases. F3 is a cytoskeleton-associated protein that plays a critical role in the regulation of cell growth, differentiation, and survival. The identification of F3 as a drug target and biomarker has significant implications for the development of new therapeutic approaches for a range of diseases.

F3 function and localization

F3 is a member of the TF family of proteins, which are known for their ability to translocate along the microtubules of cells. F3 is predominantly localized to the microtubules of actively growing cells, including neurons and muscle cells. It is involved in the regulation of cell growth, including the control of cell size, cell shape, and the distribution of cellular organelles.

F3 plays a critical role in the regulation of mitosis, the process by which a cell divides. During mitosis, F3 is involved in the maintenance of the proper structure and organization of the mitotic spindle, which is essential for the orderly separation of the chromosomes during the cell division process.

F3 is also involved in the regulation of the cytoskeleton. It helps to maintain the integrity of the cytoskeleton by participating in the regulation of the distribution of vasilium in the cytoskeleton. Vasilium is a protein that plays a critical role in the regulation of cell growth and differentiation, and its distribution is closely associated with the function of F3.

F3 as a drug target

The identification of F3 as a potential drug target has significant implications for the development of new therapeutic approaches for a range of diseases. One of the key advantages of targeting F3 is its broad specificity, meaning that it is unlikely to have unintended effects on other proteins and is likely to be well-tolerated by patients.

F3 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and developmental disorders. For example, studies have shown that F3 is involved in the regulation of cancer cell growth and has been used as a potential target for cancer therapies.

F3 has also been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells and are associated with significant morbidity and mortality.

F3 has also been shown to be involved in the development of developmental disorders, such as Down syndrome and Fragile X syndrome. These conditions are characterized by the presence of specific genetic mutations and are associated with a range of developmental and cognitive impairments.

F3 as a biomarker

In addition to its potential as a drug target, F3 has also been shown to be a useful biomarker for the diagnosis and monitoring of various diseases. For example, studies have shown that F3 levels are significantly increased in the brains of individuals with Alzheimer's disease, a condition characterized by the progressive loss of brain cells.

F3 levels have also been shown to be elevated in the brains of individuals with Parkinson's disease, a condition characterized by the progressive loss of motor neurons in the brain.

F3 has also been shown to be elevated in the blood of individuals with Down syndrome, a condition characterized by the presence of specific genetic mutations that are associated with developmental and cognitive impairments.

Conclusion

F3 is a protein that has been identified as a potential drug target and biomarker for the treatment of various human diseases. Its broad

Protein Name: Coagulation Factor III, Tissue Factor

Functions: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade

The "F3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about F3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets