Target Name: LHFPL5
NCBI ID: G222662
Review Report on LHFPL5 Target / Biomarker Content of Review Report on LHFPL5 Target / Biomarker
LHFPL5
Other Name(s): TMHS | tetraspan membrane protein of hair cell stereocilia | Deafness, autosomal recessive 67 | Tetraspan membrane protein of hair cell stereocilia | LHFP-like protein 5 | lipoma HMGIC fusion partner-like 5 protein | Lipoma HMGIC fusion partner-like 5 protein | LHFPL tetraspan subfamily member 5 | dJ510O8.8 | DFNB67 | LHFPL tetraspan subfamily member 5 protein | LHPL5_HUMAN

LHFPL5: Stimulating White Blood Cells and Promoting Blood Vessel Formation

LHFPL5 (Tumor necrosis factor-alpha-like protein 5) is a protein that is expressed in various tissues of the body, including the liver, lung, heart, and brain. It is a member of the tumor necrosis factor-alpha (TNF-alpha) family, which is a group of cytokines that play a crucial role in the immune response and tissue repair.

One of the key functions of LHFPL5 is its ability to stimulate the production of white blood cells, including natural killer cells, which are a crucial part of the immune system. LHFPL5 has also been shown to play a role in the regulation of cell growth and differentiation, and has been shown to promote the formation of new blood vessels in the liver.

Recent studies have also suggested that LHFPL5 may have potential as a drug target. For example, some researchers have shown that LHFPL5 can be overexpressed in cancer cells, and that this increase in expression can inhibit the immune response and promote tumor growth. This suggests that LHFPL5 may be a useful target for cancer therapies that aim to enhance the immune response against cancer.

Another potential use for LHFPL5 is as a biomarker for liver cancer. Some studies have shown that LHFPL5 is expressed in the liver, and that its expression levels can be used as a marker for the diagnosis and prognosis of liver cancer. This suggests that LHFPL5 may be a valuable diagnostic tool for liver cancer, and that its levels may be useful for monitoring the effectiveness of liver cancer treatments.

In addition to its potential drug and biomarker applications, LHFPL5 is also of interest to researchers because of its unique structure and biology. LHFPL5 is a member of the TNF-alpha family, and is similar to other proteins in this family, such as tumor necrosis factor-alpha (TNF-alpha) and death-in-the-mouse-hepatitis (DIMH), which are also known for their ability to stimulate the production of pro-inflammatory cytokines. This suggests that LHFPL5 may have a similar mechanism of action, and may be a useful target for drugs that aim to inhibit the production of pro-inflammatory cytokines.

Overall, LHFPL5 is a protein that has significant potential as a drug target and biomarker. Its ability to stimulate the production of white blood cells and promote the formation of new blood vessels, as well as its expression in various tissues of the body, make it an attractive target for cancer and other therapies. Further research is needed to fully understand the biology and pharmacology of LHFPL5, and to determine its full potential as a drug and biomarker.

Protein Name: LHFPL Tetraspan Subfamily Member 5

Functions: In the inner ear, may be a component of the hair cell's mechanotransduction machinery that functionally couples PCDH15 to the transduction channel. Regulates transducer channel conductance and is required for fast channel adaptation (By similarity)

The "LHFPL5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LHFPL5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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LHFPL6 | LHFPL7 | LHPP | LHX1 | LHX2 | LHX3 | LHX4 | LHX4-AS1 | LHX5 | LHX6 | LHX8 | LHX9 | LIAS | LIF | LIFR | LIFR-AS1 | LIG1 | LIG3 | LIG4 | LILRA1 | LILRA2 | LILRA3 | LILRA4 | LILRA5 | LILRA6 | LILRB1 | LILRB2 | LILRB3 | LILRB4 | LILRB5 | LILRP1 | LILRP2 | LIM domain kinase (LIMK) | LIM2 | LIMA1 | LIMASI | LIMCH1 | LIMD1 | LIMD1-AS1 | LIMD2 | LIME1 | LIMK1 | LIMK2 | LIMS1 | LIMS2 | LIMS3 | LIMS3-LOC440895 | LIMS4 | LIN28A | LIN28B | LIN28B-AS1 | LIN37 | LIN52 | LIN54 | LIN7A | LIN7B | LIN7C | LIN9 | LINC-PINT | LINC-ROR | LINC00028 | LINC00029 | LINC00032 | LINC00051 | LINC00052 | LINC00092 | LINC00102 | LINC00106 | LINC00111 | LINC00112 | LINC00113 | LINC00114 | LINC00115 | LINC00158 | LINC00159 | LINC00160 | LINC00161 | LINC00163 | LINC00173 | LINC00174 | LINC00184 | LINC00189 | LINC00200 | LINC00205 | LINC00207 | LINC00208 | LINC00210 | LINC00221 | LINC00222 | LINC00226 | LINC00235 | LINC00239 | LINC00240 | LINC00242 | LINC00243 | LINC00244 | LINC00251 | LINC00260 | LINC00261 | LINC00265