ZP1: A Potential Drug Target Or Biomarker (G22917)

Target Name: ZP1

NCBI ID: G22917

Content of Review Report on ZP1 Target / Biomarker

ZP1

ZP1: A Potential Drug Target Or Biomarker

ZP1 (Processed zona pellucida sperm-binding protein 1) is a protein that is expressed in the zona pellucida (the outer layer of the egg) of male chickens. It is a 25-kDa protein that is composed of two distinct subunits, ZP1-1 and ZP1-2. ZP1 is highly conserved across different species, and it is thought to be involved in various physiological processes in chickens, including fertilization and egg development.

Recent studies have suggested that ZP1 may have potential as a drug target or biomarker. One of the reasons for this is the fact that ZP1 is involved in several key biological processes that are important for human health, including fertility and cancer. Additionally, ZP1 has been shown to play a role in the development and progression of certain diseases, which may make it an attractive target for researchers looking for new treatments.

One of the potential benefits of targeting ZP1 is its involvement in fertilization. ZP1 is expressed in the zona pellucida and has been shown to be involved in the formation of zona pellucida-sperm interfaces, which are critical for fertilization. By blocking the activity of ZP1, researchers may be able to interfere with the process of fertilization and prevent the formation of ZP1-sperm interfaces, which could lead to infertility.

Another potential application of ZP1 is its role in cancer development. Several studies have suggested that ZP1 may be involved in the development and progression of certain cancers, including breast and prostate cancer. By targeting ZP1 with drugs or other therapeutic agents, researchers may be able to inhibit its activity and prevent the growth and progression of these diseases.

In addition to its potential as a drug target or biomarker, ZP1 has also been shown to be involved in several other physiological processes in chickens. For example, ZP1 has been shown to play a role in regulating gene expression in the zona pellucida, which may be important for the development and function of the egg. Additionally, ZP1 has been shown to be involved in the regulation of cellular signaling pathways, which may be important for the regulation of cellular processes that are important for fertilization and cancer development.

Overall, ZP1 is a protein that has the potential to be a valuable drug target or biomarker for a variety of diseases. While more research is needed to fully understand its role and potential applications, the studies that have been done so far suggest that ZP1 is an important protein that should be further investigated.

Protein Name: Zona Pellucida Glycoprotein 1

Functions: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida

The "ZP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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