Target Name: TPD52L2
NCBI ID: G7165
Review Report on TPD52L2 Target / Biomarker Content of Review Report on TPD52L2 Target / Biomarker
TPD52L2
Other Name(s): hD54 | TPD54_HUMAN | OTTHUMP00000031614 | Tumor protein D52-like 2 | OTTHUMP00000031612 | D54 | TPD54 | DKFZp686A1765 | tumor protein D52 like 2 | HCCR-binding protein 2 | TPD52 like 2, transcript variant 1 | TPD52 like 2 | OTTHUMP00000031616 | TPD52L2 variant 1 | Tumor protein D54 | Tumor protein D54 (isoform a) | OTTHUMP00000031613 | OTTHUMP00000031615 | OTTHUMP00000031617

TPD52L2 as A Potential Drug Target for Neurological Disorders

TPD52L2 (hD54), a type of gene expressed in the brain, has been identified as a potential drug target and biomarker for various neurological and psychiatric disorders. The hD54 gene is located on chromosome 11q22 and is a known regulator of the cell cycle, as well as a protein that is involved in the development and maintenance of the nervous system.

The identification of TPD52L2 as a potential drug target and biomarker for neurological and psychiatric disorders has been the focus of extensive research in recent years, and there is growing evidence to support this hypothesis. One of the key findings of this research is that TPD52L2 is involved in the development and progression of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other forms of dementia.

In addition to its involvement in the development of these disorders, TPD52L2 is also shown to be involved in the regulation of the brain cell cycle, which is a critical process for the growth, development, and function of neurons. Studies have shown that TPD52L2 plays a role in the regulation of the cell cycle by controlling the movement of chromatin into the cytoplasm, where it is accessible to the microtubules of the mitotic spindle, which are responsible for organizing the chromosomes in the cell.

Furthermore, TPD52L2 is also shown to be involved in the regulation of the actin filament, which is a protein that helps to keep the cells in a fixed position and is involved in many cellular processes, including the movement of neurons. Studies have shown that TPD52L2 plays a role in the regulation of the actin filament by interacting with the protein tyrosine kinase, which is involved in the regulation of the actin filament.

In addition to its involvement in the regulation of the cell cycle and actin filament, TPD52L2 is also shown to be involved in the regulation of the microtubules, which are small structures that are involved in the movement of cells and are made up of protein and polymer filaments. Studies have shown that TPD52L2 plays a role in the regulation of the microtubules by interacting with the protein tau, which is a component of the microtubules and is involved in the regulation of the cell cycle.

Given the involvement of TPD52L2 in the regulation of the cell cycle, it is a potential drug target for a variety of neurological and psychiatric disorders. One of the key challenges in developing a drug target for TPD52L2 is the development of effective techniques for its targeting, such as small interfering RNA (siRNA) screening and gene editing techniques. Once its role in the regulation of the cell cycle has been established, further studies can focus on identifying potential drug targets for TPD52L2 and developing effective therapies for the treatment of neurological and psychiatric disorders associated with its dysfunction.

In conclusion, TPD52L2 is a gene that has been shown to be involved in the regulation of the cell cycle and the actin filament, as well as the regulation of the microtubules. Its potential as a drug target and biomarker for neurological and psychiatric disorders has been the focus of extensive research in recent years, and there is growing evidence to support this hypothesis. Further studies are needed to develop effective therapies for the treatment of these disorders based on TPD52L2 as a drug target and biomarker.

Protein Name: TPD52 Like 2

The "TPD52L2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TPD52L2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TPD52L3 | TPGS1 | TPGS2 | TPH1 | TPH2 | TPI1 | TPI1P1 | TPI1P2 | TPI1P3 | TPK1 | TPM1 | TPM2 | TPM3 | TPM3P5 | TPM3P7 | TPM3P9 | TPM4 | TPMT | TPO | TPP1 | TPP2 | TPPP | TPPP2 | TPPP3 | TPR | TPRA1 | TPRG1 | TPRG1-AS1 | TPRG1-AS2 | TPRG1L | TPRKB | TPRN | TPRX1 | TPRXL | TPSAB1 | TPSB2 | TPSD1 | TPSG1 | TPST1 | TPST2 | TPST2P1 | TPT1 | TPT1-AS1 | TPT1P6 | TPT1P8 | TPT1P9 | TPTE | TPTE2 | TPTE2P1 | TPTE2P2 | TPTE2P3 | TPTE2P4 | TPTE2P5 | TPTE2P6 | TPTEP1 | TPTEP2 | TPTEP2-CSNK1E | TPX2 | TRA2A | TRA2B | TRABD | TRABD2A | TRABD2B | TRAC | TRADD | TRAF1 | TRAF2 | TRAF3 | TRAF3IP1 | TRAF3IP2 | TRAF3IP2-AS1 | TRAF3IP3 | TRAF4 | TRAF5 | TRAF6 | TRAF7 | TRAFD1 | TRAIP | TRAJ1 | TRAJ10 | TRAJ11 | TRAJ12 | TRAJ13 | TRAJ14 | TRAJ15 | TRAJ16 | TRAJ17 | TRAJ18 | TRAJ19 | TRAJ2 | TRAJ20 | TRAJ21 | TRAJ22 | TRAJ23 | TRAJ24 | TRAJ25 | TRAJ26 | TRAJ27 | TRAJ28 | TRAJ29