HAAO: A Protein Regulator of The Blood-Brain Barrier and Neurocircuits

Target Name: HAAO

NCBI ID: G23498

HAAO

HAAO: A Protein Regulator of The Blood-Brain Barrier and Neurocircuits

HAAO (3-HAO) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a key regulator of the blood-brain barrier, which is a barrier that separates the brain from the rest of the body and is responsible for maintaining the integrity of the nervous system.

HAAO is composed of three subunits, each of which has a distinct function in regulating the blood-brain barrier. The first subunit, HAAO1, is a transmembrane protein that is involved in the regulation of ion channels and is thought to play a role in the regulation of brain function. The second subunit, HAAO2, is a cytoplasmic protein that is involved in the regulation of cell signaling pathways and is thought to be involved in the regulation of neural circuits. The third subunit, HAAO3, is a cytoplasmic protein that is involved in the regulation of inflammation and is thought to be involved in the regulation of immune responses.

HAAO is a protein that is expressed in a wide range of tissues throughout the body, including the brain, heart, kidneys, and liver. It is a key regulator of the blood-brain barrier, which is a barrier that separates the brain from the rest of the body and is responsible for maintaining the integrity of the nervous system.

HAAO is thought to be involved in a wide range of physiological processes in the body. For example, it is involved in the regulation of ion channels, which are proteins that allow charged particles to enter or exit cells. This is important for the regulation of brain function, as channels play a critical role in the transmission of electrical signals throughout the nervous system.

HAAO is also involved in the regulation of cell signaling pathways, which are the processes by which cells communicate with one another. This is important for the regulation of neural circuits, which are the networks of neurons that are responsible for the processing of information and the coordination of neural activity.

In addition to its role in the regulation of the blood-brain barrier and neural circuits, HAAO is also thought to be involved in the regulation of inflammation. This is important for the regulation of immune responses, as inflammation can be a harmful response to the presence of foreign substances in the body.

Overall, HAAO is a protein that is involved in a wide range of physiological processes in the body. It is a potential drug target and may be useful for the treatment of a variety of conditions, including neurological and inflammatory diseases.

Protein Name: 3-hydroxyanthranilate 3,4-dioxygenase

Functions: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate

The "HAAO Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HAAO comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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