Target Name: HAGH
NCBI ID: G3029
Review Report on HAGH Target / Biomarker Content of Review Report on HAGH Target / Biomarker
HAGH
Other Name(s): Acetoacetylglutathione hydrolase | Hydroxyacylglutathione hydrolase, mitochondrial (isoform 2) | hydroxyacylglutathione hydroxylase | Glx II | Hydroxyacylglutathione hydrolase, mitochondrial | HAGH1 | GLX2 | Cytosolic glyoxalase II | S-2-hydroxylacylglutathione hydrolase | hydroxyacylglutathione hydrolase | GLO2 | Hydroxyacylglutathione hydrolase | glyoxalase II | GLXII | GLO2_HUMAN | HAGH variant 2 | Glyoxalase II | Hydroxyacylglutathione hydroxylase | Hydroxyacylglutathione hydrolase, transcript variant 2

HAGH: A Potential Drug Target and Biomarker

Haglox (HAGH) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of the immune response and has been implicated in a number of diseases, including autoimmune disorders, neurodegenerative diseases, and cancer. In recent years, research has focused on understanding the role of HAGH in these conditions and using it as a potential drug target.

One of the key functions of HAGH is its role in regulating the immune response. It is known to play a key role in the regulation of T cell development and function, as well as the regulation of inflammation. HAGH has been shown to be involved in the development of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. It has also been shown to be involved in the regulation of cancer risk, by helping to prevent the development of cancer cells.

Another function of HAGH is its role in regulating blood pressure. It has been shown to play a key role in the regulation of blood pressure, by helping to constrict blood vessels and regulate blood flow. This can help to prevent the development of cardiovascular disease, which is a major risk factor for many diseases, including heart failure and stroke.

HAGH has also been shown to be involved in the regulation of bone density, which is important for maintaining strong bones and a healthy immune system. It has been shown to play a key role in the regulation of bone density, by helping to maintain the activity of enzymes that are involved in bone formation. This can help to prevent the development of osteoporosis, which is a condition in which the bones become weak and fragile due to a loss of bone mass.

In addition to its role in regulating the immune response, HAGH has also been shown to be involved in the regulation of a number of other biological processes, including cell signaling, DNA replication, and cell division. It is also known to play a key role in the regulation of the blood-brain barrier, which is the barrier that separates the brain from the body and helps to protect it from harmful substances.

Given the wide range of functions that HAGH is involved in, it is a promising target for drug development. Researchers have been exploring the use of drugs that target HAGH, in order to treat a variety of conditions, including autoimmune disorders, neurodegenerative diseases, and cancer. Some studies have shown that these drugs can be effective in treating these conditions, and further research is needed to fully understand their potential.

In addition to its potential as a drug target, HAGH is also a potential biomarker. Researchers have been exploring the use of HAGH as a biomarker for a number of conditions, including autoimmune disorders, neurodegenerative diseases, and cancer. Some studies have shown that HAGH can be used as a biomarker for these conditions, and further research is needed to fully understand its potential.

Overall, HAGH is a protein that is involved in a wide range of biological processes, including the regulation of the immune response, blood pressure, and bone density. Its potential as a drug target and biomarker make it an attractive target for further research. Further studies are needed to fully understand its role in these conditions and to develop drugs that can effectively treat them.

Protein Name: Hydroxyacylglutathione Hydrolase

Functions: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid

The "HAGH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HAGH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

HAGHL | HAGLR | HAGLROS | HAL | HAMP | HAND1 | HAND2 | HAND2-AS1 | HAO1 | HAO2 | HAO2-IT1 | HAP1 | HAPLN1 | HAPLN2 | HAPLN3 | HAPLN4 | HAPSTR1 | HAR1A | HAR1B | HARBI1 | HARS1 | HARS2 | HAS1 | HAS2 | HAS2-AS1 | HAS3 | HASPIN | HAT1 | HAUS1 | HAUS1P1 | HAUS2 | HAUS3 | HAUS4 | HAUS5 | HAUS6 | HAUS7 | HAUS8 | HAVCR1 | HAVCR1P1 | HAVCR2 | HAX1 | HAX1P1 | HBA1 | HBA2 | HBAP1 | HBB | HBBP1 | HBD | HBE1 | HBEGF | HBG1 | HBG2 | HBM | HBO1 complex | HBP1 | HBQ1 | HBS1L | HBZ | HBZP1 | HCAR1 | HCAR2 | HCAR3 | HCCAT5 | HCCS | HCFC1 | HCFC1R1 | HCFC2 | HCG11 | HCG14 | HCG15 | HCG17 | HCG18 | HCG20 | HCG21 | HCG22 | HCG23 | HCG25 | HCG26 | HCG27 | HCG4 | HCG4B | HCG4P11 | HCG4P3 | HCG4P5 | HCG4P8 | HCG9 | HCGVIII-2 | HCK | HCLS1 | HCN1 | HCN2 | HCN3 | HCN4 | HCP5 | HCRT | HCRTR1 | HCRTR2 | HCST | HDAC1 | HDAC10