HAPLN2: A Potential Drug Target Or Biomarker (G60484)

Target Name: HAPLN2

NCBI ID: G60484

HAPLN2

HAPLN2: A Potential Drug Target Or Biomarker

HAPLN2, also known as HPLN2_HUMAN, is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

HAPLN2 is a non-coding RNA molecule that is expressed in various tissues and cells of the body. It is a key regulator of the hematopoietic stem cell (HSC) lineage, which is responsible for the production of all blood cells. HAPLN2 has been shown to play a role in the regulation of cell growth, differentiation, and survival, and is often dysregulated in various diseases.

One of the key features of HAPLN2 is its ability to induce cell proliferation both in healthy tissues and in cancer cells. Studies have shown that HAPLN2 can promote the growth of various types of cancer cells, including breast, lung, and ovarian cancer cells. This makes it a potential drug target for cancer treatment.

Another promising aspect of HAPLN2 is its ability to regulate the expression of genes involved in cell adhesion, migration, and invasion. This is important for the development of cancer, as these processes are often disrupted in cancer cells. HAPLN2 has been shown to play a role in regulating the expression of genes involved in cell adhesion and migration, which may make it a useful biomarker for tracking the progression of cancer.

HAPLN2 has also been shown to be involved in the regulation of cellular stress responses, which are important for the survival of cells under stressful conditions. Studies have shown that HAPLN2 can help cells cope with stress, including oxidative stress, apoptosis, and DNA damage. This may make it a useful target for interventions aimed at preventing cellular stress and promoting cellular survival.

In addition to its potential as a drug target or biomarker, HAPLN2 is also of interest as a potential therapeutic agent. Studies have shown that HAPLN2 can be downregulated by various techniques, including RNA interference and small interfering RNA (siRNA). This makes it a potential target for therapeutic intervention.

Overall, HAPLN2 is a gene that has the potential to be a drug target or biomarker for various diseases. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a therapeutic agent.

Protein Name: Hyaluronan And Proteoglycan Link Protein 2

Functions: Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid (By similarity)

The "HAPLN2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HAPLN2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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