EPHA10: A Potential Drug Target for Tissue Development and Maintenance

Target Name: EPHA10

NCBI ID: G284656

EPHA10

EPHA10: A Potential Drug Target for Tissue Development and Maintenance

The EPHA10 (EPH receptor A10, transcript variant 2) is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It is a member of the Eph receptor tyrosine kinase family, which is a group of transmembrane proteins that play a crucial role in the development and maintenance of tissues and organs.

EPHA10 has been identified as a potential drug target due to its involvement in several cellular processes, including cell signaling, angiogenesis, and wound healing. It is also expressed in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

During the development and maintenance of tissues and organs, EPH signaling pathways are involved in the regulation of cell proliferation, differentiation, and survival. The Eph receptor tyrosine kinase family plays a central role in these processes by regulating the levels of intracellular signaling molecules, such as phosphatidylserine (PS) and sonic hedgehog (SHH).

EPHA10 is a 21-kDa transmembrane protein that is expressed in various tissues, including the skin, hair, and nails. It is a member of the Eph receptor tyrosine kinase family and has been shown to play a role in several cellular processes, including cell signaling, angiogenesis, and wound healing.

EPHA10 functions as a receptor for the tyrosine kinase Repto-transformer kinase (RTK), which is a protein that is involved in the regulation of cellular processes, including cell signaling and angiogenesis. Repto-transformer kinase is a protein that is highly expressed in tumors An anti-tumor protein with cell-inhibitory effects, which may be a potential drug target for cancer treatment.

In addition to its role in RTK regulation, EPHA10 has also been shown to play a role in several other cellular processes. For example, it is involved in the regulation of cell adhesion, migration, and the formation of tight junctions in epithelial cells. It is also involved in the regulation of ion channels, including the production of action potentials in neurons.

EPHA10 has also been shown to be involved in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, it has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. It is also involved in the regulation of wound healing and has been shown to play a role in the regulation of tissue repair processes.

EPHA10 is also a potential biomarker for several diseases, including cancer. Its expression has been shown to be elevated in several types of cancer, including breast cancer, lung cancer, and colon cancer. This suggests that EPHA10 may be a useful biomarker for the diagnosis and prognosis of these diseases.

In conclusion, EPHA10 is a protein that is involved in several cellular processes that are important for the development and maintenance of tissues and organs. Its involvement in RTK regulation and its potential as a drug target make it a promising target for the development of new therapies for a variety of diseases. Further research is needed to fully understand the role of EPHA10 in these processes and to develop effective treatments.

Protein Name: EPH Receptor A10

Functions: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5

The "EPHA10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EPHA10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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