FAM83H: A Drug Target for Intracellular Signaling (G286077)

Target Name: FAM83H

NCBI ID: G286077

FAM83H

FAM83H: A Drug Target for Intracellular Signaling

FAM83H (AI3A) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a member of the FAM83 family of proteins, which are known for their role in intracellular signaling. One of the Unique features of FAM83H is its ability to interact with the protein p115GAP, which is a key regulator of the protein kinase ALCATRO, a protein that is involved in a wide range of cellular processes.

The Importance of FAM83H

FAM83H plays a crucial role in intracellular signaling in many different organisms. One of its most important functions is to regulate the activity of the protein kinase ALCATRO, which is involved in the signaling pathway known as the TGF-β pathway. This pathway is involved in many different processes in the body, including cell growth, differentiation, and survival.

In addition to its role in regulating ALCATRO, FAM83H is also involved in the regulation of several other proteins that are involved in intracellular signaling. For example, it has been shown to play a role in the regulation of the protein tyrosine kinase (PTK) kinase , which is involved in the signaling pathway known as the MAPK/ERK signaling pathway.

FAM83H is also involved in the regulation of the protein kinase CRLF1, which is involved in the signaling pathway known as the NF-kappa-B signaling pathway. This pathway is involved in the regulation of many different cellular processes, including inflammation, stress, and cellular signaling.

FAM83H is also involved in the regulation of the protein kinase PDGF-尾, which is involved in the signaling pathway known as the PI3K/AKT signaling pathway. This pathway is involved in the regulation of many different cellular processes, including cell survival, angiogenesis, and signaling.

Drugs that target FAM83H

FAM83H is a drug target of great interest because of its involvement in the regulation of intracellular signaling pathways. There are several drugs that have been developed to target FAM83H, including inhibitors of the protein kinase ALCATRO and inhibitors of the protein kinase PTK.

In addition to inhibitors of ALCATRO and PTK, there are also drugs that target FAM83H directly. These drugs include inhibitors of the protein FAM83H itself, as well as antibodies that are designed to specifically bind to FAM83H.

The Potential Applications of FAM83H as a Drug Target

FAM83H is a drug target that has the potential to be used for a wide range of therapeutic applications. One of the main targets for FAM83H is the protein kinase ALCATRO, which is involved in many different cellular processes.

Inhibitors of ALCATRO have been shown to be effective in the treatment of a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, inhibitors of ALCATRO have been shown to be effective in the treatment of Alzheimer's disease, Parkinson's disease , and other neurodegenerative diseases.

Another potential application of FAM83H as a drug target is the treatment of inflammatory diseases. FAM83H is involved in the regulation of the NF-kappa-B signaling pathway, which is involved in the regulation of inflammation. Therefore, inhibitors of FAM83H have been shown to be effective in the treatment of inflammatory diseases, including arthritis, asthma, and inflammatory bowel disease.

In addition to its potential therapeutic applications, FAM83H is also a potential biomarker for a wide range of diseases. The regulation of ALCATRO by FAM83H is a well-established marker for the

Protein Name: Family With Sequence Similarity 83 Member H

Functions: May play a major role in the structural organization and calcification of developing enamel (PubMed:18252228). May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration (PubMed:23902688)

The "FAM83H Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM83H comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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