FAM86HP: A Potential Drug Target and Biomarker for Family with Sequence Similarity 86

Target Name: FAM86HP

NCBI ID: G729375

FAM86HP

Other Name(s): family with sequence similarity 86 member H, pseudogene | Family with sequence similarity 86, member A pseudogene

FAM86HP: A Potential Drug Target and Biomarker for Family with Sequence Similarity 86

FAM86 is a gene family that encodes for a protein with sequence similarity 86 (SS86) members. The protein encoded by FAM86 is a key regulator of cell adhesion and signaling, and is involved in various physiological processes, including embryonic development, tissue repair, and cancer progression. The discovery of the FAM86 gene family has generated a great deal of interest in the potential implications for human disease, including the development of new drugs and biomarkers. In this article, we will explore the FAM86 gene family, with a focus on its potential as a drug target and biomarker.

FAM86 Genetics

The FAM86 gene family was identified through bioinformatics analysis of human genomic DNA. The gene family consists of 22 members, with each member encoding a unique protein with sequence similarity 86. The majority of the FAM86 genes are located on chromosome 16, with the remaining genes located on chromosomes 1, 3, 5, 7, 10, and 12.

Function and Interaction

The FAM86 protein is a key regulator of cell adhesion and signaling, involved in processes such as embryonic development, tissue repair, and cancer progression. It is composed of a transmembrane domain, a cytoplasmic domain, and an extracellular domain. The transmembrane domain is responsible for the protein's anion-like behavior, while the cytoplasmic domain is involved in protein-protein interactions. The extracellular domain is involved in the protein's interactions with ligands and other proteins, including its role in cell adhesion.

The FAM86 gene is expressed in various tissues and organs, including brain, heart, kidney, and cancer cells. It is also involved in various signaling pathways, including the TGF-β pathway, which plays a key role in regulating cell growth and differentiation.

Drug Target Potential

The FAM86 protein is a potential drug target due to its involvement in various signaling pathways. Several studies have shown that inhibitors of FAM86 can suppress the activity of various signaling pathways, including the TGF-β pathway. These inhibitors have been shown to have therapeutic effects in various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

In addition to its potential as a drug target, the FAM86 protein is also a potential biomarker for certain diseases. The FAM86 gene is expressed in various tissues and organs, including brain, heart, and cancer cells. Therefore, measuring the expression of FAM86 in these tissues and cells could be a useful diagnostic or predictive marker for various diseases. For example, reduced FAM86 expression has been shown to be associated with poor prognosis in neurodegenerative diseases, while increased FAM86 expression has been associated with cancer.

Conclusion

In conclusion, the FAM86 gene family is a promising candidate for drug targeting and biomarker research. Its encoded protein is involved in various physiological processes, including cell adhesion and signaling, and is expressed in various tissues and organs. The discovery of the FAM86 gene family has generated a great deal of interest in the potential implications for human disease, including the development of new drugs and biomarkers. Further research is needed to fully understand the role of the FAM86 gene family in various physiological processes and to explore its potential as a drug target and biomarker.

Protein Name: Family With Sequence Similarity 86 Member H, Pseudogene

The "FAM86HP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM86HP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets