Target Name: FANCA
NCBI ID: G2175
Review Report on FANCA Target / Biomarker Content of Review Report on FANCA Target / Biomarker
FANCA
Other Name(s): FANCA_HUMAN | FACA | Fanconi anemia group A protein (isoform a) | FA complementation group A, transcript variant 3 | FA-H | Protein FACA | FANCA variant 1 | FA | FA1 | Fanconi anemia, type 1 | Fanconi anemia group A protein (isoform c) | FAH | FANCA variant 3 | Fanconi anemia group A protein | Fanconi anemia, complementation group H | FA complementation group A, transcript variant 1 | Fanconi anemia complementation group A | FAA | FA complementation group A | FANCH

FanCa: A Protein with Potential as A Drug Target and Biomarker

FanCa (FANCA_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and liver. It is a key regulator of the blood-brain barrier, which is a specialized barrier that separates the brain from the rest of the body and helps to protect it from harmful substances.

FanCa has been identified as a potential drug target for a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its role in these conditions has been explored in a number of studies, and its potential as a drug has generated a lot of interest.

One of the key reasons for the interest in FanCa is its ability to interact with a variety of different proteins. This makes it a potential candidate for drugs that can modulate its activity and potentially interfere with its functions. For example, studies have shown that FanCa can interact with the protein PDGF-BB, which is involved in the development and treatment of cancer.

FanCa has also been shown to play a role in the regulation of cellular processes that are important for brain function. For example, it has been shown to be involved in the regulation of the blood-brain barrier, which is responsible for controlling the movement of substances into and out of the brain. This is important for the brain's ability to function properly, and is a potential target for drugs that can modulate its activity.

Another promising aspect of FanCa is its ability to be targeted by small molecules. This is because its structure is relatively simple, and the use of small molecules has been shown to be effective in modulating its activity. This is important for the development of drugs that can specifically target FanCa and modulate its function.

In addition to its potential as a drug target, FanCa is also a potential biomarker. Its expression has been shown to be elevated in a variety of conditions, including cancer, neurodegenerative disorders, and autoimmune diseases. This makes it a potential indicator of the presence of these conditions and could be used as a diagnostic tool.

Overall, FanCa is a protein that has a lot of potential as a drug target and biomarker. Its structure is relatively simple, which makes it a potential candidate for small molecules. Its role in the regulation of the blood-brain barrier and its ability to be targeted by these molecules make it a promising candidate for drugs that can modulate its function. Further research is needed to fully understand its potential as a drug and biomarker.

Protein Name: FA Complementation Group A

Functions: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability

The "FANCA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FANCA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FANCB | FANCC | FANCD2 | FANCD2OS | FANCE | FANCF | FANCG | FANCI | FANCL | FANCM | Fanconi anemia complex | FANK1 | FAP | FAR1 | FAR2 | FAR2P1 | FAR2P2 | FARP1 | FARP2 | FARS2 | FARS2-AS1 | FARSA | FARSB | FAS | FAS-AS1 | FASLG | FASN | FASTK | FASTKD1 | FASTKD2 | FASTKD3 | FASTKD5 | FAT1 | FAT2 | FAT3 | FAT4 | FATE1 | Fatty Acid Binding Protein | Fatty acid desaturase | FAU | FAUP1 | FAUP4 | FAXC | FAXDC2 | FBF1 | FBH1 | FBL | FBLIM1 | FBLL1 | FBLN1 | FBLN2 | FBLN5 | FBLN7 | FBN1 | FBN2 | FBN3 | FBP1 | FBP2 | FBRS | FBRSL1 | FBXL12 | FBXL13 | FBXL14 | FBXL15 | FBXL16 | FBXL17 | FBXL18 | FBXL19 | FBXL19-AS1 | FBXL2 | FBXL20 | FBXL21P | FBXL22 | FBXL3 | FBXL4 | FBXL5 | FBXL6 | FBXL7 | FBXL8 | FBXL9P | FBXO10 | FBXO11 | FBXO15 | FBXO16 | FBXO17 | FBXO2 | FBXO21 | FBXO22 | FBXO24 | FBXO25 | FBXO27 | FBXO28 | FBXO3 | FBXO30 | FBXO31 | FBXO32 | FBXO33 | FBXO34 | FBXO36 | FBXO38