FAT2: A Potential Drug Target for Obesity and Diabetes (G2196)

Target Name: FAT2

NCBI ID: G2196

FAT2

FAT2: A Potential Drug Target for Obesity and Diabetes

FAT2, also known as hFat2, is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including obesity, type 2 diabetes, and certain cardiovascular conditions.

FAT2 is a gene that encodes a protein known as fat-soluble adaptor protein 2. The protein produced by FAT2 helps to transport fat molecules from the bloodstream to the liver, where they can be used for energy or stored as fat.

Research has shown that individuals with certain genetic variations in the FAT2 gene are at an increased risk of developing obesity and type 2 diabetes. This is because these individuals have reduced levels of the fat-soluble adaptor protein 2, which can make it difficult for the body to effectively transport fat molecules to the liver for energy or storage.

In addition to its role in obesity and type 2 diabetes, FAT2 has also been shown to be involved in the development and progression of certain cardiovascular conditions, such as heart failure and certain types of cancer.

As a potential drug target, FAT2 is being studied for its potential to treat obesity and type 2 diabetes by manipulating the levels of the fat-soluble adaptor protein 2 in the body. For example, researchers have shown that increasing the levels of this protein can help to reduce the amount of fat stored in the body and improve insulin sensitivity, which can lead to better management of both obesity and type 2 diabetes.

FAT2 has also been shown to be a potential biomarker for certain diseases, such as heart failure and certain types of cancer. This is because the levels of the fat-soluble adaptor protein 2 are often reduced in individuals with these conditions, and can serve as a marker for the severity and progression of these diseases.

Overall, FAT2 is a gene that has the potential to be a drug target or biomarker for the treatment of various diseases. Further research is needed to fully understand its role and potential applications in medicine.

Protein Name: FAT Atypical Cadherin 2

Functions: Involved in the regulation of cell migration (PubMed:18534823). May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development (By similarity)

The "FAT2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAT2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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