FAM90A13P: A Potential Drug Target and Biomarker (G441314)

Target Name: FAM90A13P

NCBI ID: G441314

FAM90A13P

Other Name(s): FAM90A13 | family with sequence similarity 90 member A13, pseudogene | Family with sequence similarity 90, member A13, pseudogene

FAM90A13P: A Potential Drug Target and Biomarker

Abstract:

FAM90A13P, a protein expressed in various tissues of the human body, has been identified as a potential drug target and biomarker. Its unique structure and various post-translational modifications (PTMs) have led to its high stability and stability in various cellular environments, making it an attractive target for small molecules. This review article aims to provide an overview of FAM90A13P, including its structure, function, and potential as a drug target and biomarker.

Introduction:

FAM90A13P is a protein that can be found in various tissues of the human body, including muscle, heart, liver, and brain. It is a member of the FAM90A family, which includes several related proteins that share similar sequence and structural characteristics. FAM90A13P is Characterized by its unique structure, which consists of a long amino acid sequence with a variety of post-translational modifications (PTMs).

Structure and Function:

FAM90A13P has a characteristic alpha-helical structure, with a distinct N-terminus and a C-terminus. The protein is highly stable in various cellular environments, including high salt, high temperature, and extreme pH values. This stability is due to several factors , including the presence of multiple PTMs, such as phosphorylation, acetylation, and polyglutamylation, which have been identified in various studies.

FAM90A13P functions as a protein that plays a role in various cellular processes, including cell signaling, apoptosis, and inflammation. It is involved in several signaling pathways, including the TGF-β pathway, which is involved in cell signaling and growth, and the PI3K /Akt pathway, which is involved in cell survival and angiogenesis.

FAM90A13P has also been identified as a potential drug target due to its unique structure and post-translational modifications. Its stability in various cellular environments makes it an attractive target for small molecules that can modulate its activity. Additionally, its involvement in multiple signaling pathways makes it a potential biomarker for various diseases.

Potential as a Drug Target:

FAM90A13P's unique structure and post-translational modifications make it an attractive target for small molecules. Several studies have shown that small molecules can modulate the activity of FAM90A13P, leading to changes in cellular behavior and biology.

One of the most promising small molecules for modulating FAM90A13P's activity is a class of drugs called IDMs (Inositol-Derived Macrolides). IDMs are a type of small molecule that can bind to various protein targets, including FAM90A13P. Several IDMs, including N-Acetyl -L-Tryptophan (NALT), have been shown to modulate the activity of FAM90A13P, leading to changes in cellular behavior and biology.

Another class of small molecules that may be effective in modulating FAM90A13P's activity is the class of drugs called inhibitors of protein-protein interactions (IPIs). IPIs are a type of small molecules that can bind to various protein-protein interaction sites, including FAM90A13P. Several IPIs, including S100 and S100-2, have been shown to modulate the activity of FAM90A13P, leading to changes in cellular behavior and biology.

FAM90A13P has also been shown to interact with small molecules that are involved in the regulation of cellular processes, including cell signaling, apoptosis, and inflammation. For example, FAM90A13P has been shown to interact with the protein

Protein Name: Family With Sequence Similarity 90 Member A13, Pseudogene

The "FAM90A13P Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM90A13P comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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