HNMT: A Potential Drug Target for Neurological Disorders (G3176)

Target Name: HNMT

NCBI ID: G3176

HNMT

HNMT: A Potential Drug Target for Neurological Disorders

HNMT (HNMT_HUMAN), also known as human N-methyl-D-aspartate (HNMT), is a protein that is expressed in various tissues of the human body. It is a key player in the regulation of neural signaling, and its levels have been linked to a number of neurological and psychiatric disorders. As a result, HNMT has generated a lot of interest as a potential drug target or biomarker.

HNMT is a transmembrane protein that is involved in the regulation of several intracellular signaling pathways. It is a key component of the neurotransmitter transporter system, which is responsible for the delivery of neurotransmitters across the blood-brain barrier. HNMT is involved in the transport of several neurotransmitters, including dopamine, serotonin, and endocannabinoids.

HNMT has also been shown to be involved in the regulation of ion channels, including the action potential generation and propagation. Its expression has been observed in various neural tissues, including the brain, spinal cord, and retina. HNMT has been shown to play a role in the regulation of neuronal excitability, and its levels have been linked to the manifestation of neurological disorders.

One of the most promising aspects of HNMT is its potential as a drug target. The use of small molecules to modulate HNMT activity has been shown to be effective in animal models of several neurological disorders, including depression, anxiety, and schizophrenia. HNMT has also been shown to be a promising biomarker for several neurological disorders, including Alzheimer's disease and Parkinson's disease.

HNMT has also been shown to play a role in the regulation of pain perception. Its expression has been observed in various pain-sensitive tissues, including the skin and gut. HNMT has been shown to play a role in the regulation of pain modulation, and its levels have been linked to the manifestation of chronic pain.

In addition to its potential as a drug target or biomarker, HNMT has also been shown to have a number of potential therapeutic applications. For example, HNMT has been shown to be involved in the regulation of neuronal communication, and its inhibition has been shown to have therapeutic effects on anxiety and depression. HNMT has also been shown to play a role in the regulation of inflammation, and its inhibition has been shown to have therapeutic effects on pain and neurodegenerative diseases.

Overall, HNMT is a protein that has a lot of potential as a drug target or biomarker. Its involvement in the regulation of neural signaling and its expression in various tissues make it an attractive target for small molecule manipulation. Further research is needed to fully understand the role of HNMT in neurological and psychiatric disorders, and to develop safe and effective therapies based on its modulation.

Protein Name: Histamine N-methyltransferase

Functions: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine

The "HNMT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HNMT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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