Target Name: HOMEZ
NCBI ID: G57594
Review Report on HOMEZ Target / Biomarker Content of Review Report on HOMEZ Target / Biomarker
HOMEZ
Other Name(s): Homeobox and leucine zipper encoding | Homeobox and leucine zipper protein Homez | homeodomain leucine zipper-containing factor | homeobox and leucine zipper encoding | Homeodomain leucine zipper-containing factor | KIAA1443 | HOMEZ_HUMAN

HOMEZ: A Protein in Gene Expression and Cellular Processes Essential for Human Health and Survival

HOMEZ (Homeobox and Leucine Zipper Encoding) is a protein that is expressed in various tissues of the human body, including the brain, heart, and muscle. It is a key regulator of gene expression and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders. While the exact function of HOMEZ is not yet fully understood, research has shown that it plays a crucial role in the regulation of cellular processes that are essential for human health and survival.

Recent studies have identified potential drug targets and biomarkers for HOMEZ, providing hope for the development of new treatments for a range of diseases. In this article, we will explore the current state of research on HOMEZ and its potential as a drug target.

Expression and Localization

HOMEZ is a member of the homeobox gene family, which is a family of developmentally conserved genes. Homeobox genes encode a variety of proteins that are involved in the regulation of gene expression and cellular processes that are essential for normal development and function. HOMEZ is a 21-kDa protein that is expressed in a variety of tissues, including the brain, heart, and muscle.

HOMEZ is highly localized to the cytoplasm of cells, where it is involved in the regulation of cellular processes that are essential for normal cell function. It has been shown to be expressed in a variety of tissues and cells, including neurons, astrocytes, and pericytes . It is also expressed in the placenta, which plays a critical role in the development and maintenance of fetal tissues.

Functions and Implications

HOMEZ is involved in a number of cellular processes that are essential for human health and survival. One of its most well-known functions is its role in the regulation of cellular processes that are critical for normal brain development and function. HOMEZ has been shown to play a crucial role in the development and maintenance of neural stem cells, which are a critical cell type that are involved in the development and repair of tissues in the brain.

HOMEZ is also involved in the regulation of cellular processes that are critical for normal heart function. It has been shown to play a role in the regulation of ion channels in heart cells, which are involved in the flow of electrical current through the heart.

In addition to its role in cellular processes, HOMEZ is also a potential drug target. Its localization to the cytoplasm and its involvement in a variety of cellular processes make it an attractive target for small molecules that can modulate its activity.

Drugs that Target HOMEZ

Several drugs have been shown to target HOMEZ, providing hope for the development of new treatments for a range of diseases. One of the most well-known drugs is rapamycin, which is an inhibitor of the mTOR pathway. Rapamycin has been shown to inhibit the activity of HOMEZ and has been shown to be effective in treating a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

Another drug that has been shown to target HOMEZ is valproic acid, which is an inhibitor of the poly (ADP-ribose) polymerase (PARP). PARP is an enzyme that is involved in the regulation of DNA replication and has been implicated in a variety of diseases, including cancer. Valproic acid has been shown to inhibit the activity of HOMEZ and has been shown to be effective in treating a variety of diseases, including cancer.

Other drugs that have been shown to target HOMEZ include 5-fluorouracil (5-FU), which is a chemotherapy drug that is used to treat a variety of cancers; and th

Protein Name: Homeobox And Leucine Zipper Encoding

Functions: May function as a transcriptional regulator

The "HOMEZ Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HOMEZ comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

HOOK1 | HOOK2 | HOOK3 | Hop2-Mnd1 complex | HOPX | HORMAD1 | HORMAD2 | HORMAD2-AS1 | HOTAIR | HOTAIRM1 | HOTTIP | HOXA-AS2 | HOXA-AS3 | HOXA1 | HOXA10 | HOXA10-AS | HOXA10-HOXA9 | HOXA11 | HOXA11-AS | HOXA13 | HOXA2 | HOXA3 | HOXA4 | HOXA5 | HOXA6 | HOXA7 | HOXA9 | HOXB-AS1 | HOXB-AS3 | HOXB1 | HOXB13 | HOXB2 | HOXB3 | HOXB4 | HOXB5 | HOXB6 | HOXB7 | HOXB8 | HOXB9 | HOXC-AS1 | HOXC-AS2 | HOXC-AS3 | HOXC10 | HOXC11 | HOXC12 | HOXC13 | HOXC13-AS | HOXC4 | HOXC5 | HOXC6 | HOXC8 | HOXC9 | HOXD-AS2 | HOXD1 | HOXD10 | HOXD11 | HOXD12 | HOXD13 | HOXD3 | HOXD4 | HOXD8 | HOXD9 | HP | HP1BP3 | HPCA | HPCAL1 | HPCAL4 | HPD | HPDL | HPF1 | HPGD | HPGDS | HPN | HPN-AS1 | HPR | HPRT1 | HPRT1P2 | HPS1 | HPS3 | HPS4 | HPS5 | HPS6 | HPSE | HPSE2 | HPX | HPYR1 | HR | HRAS | HRC | HRCT1 | HRG | HRH1 | HRH2 | HRH3 | HRH4 | HRK | HRNR | HROB | HS1BP3 | HS1BP3-IT1