HOX-A2: A Key Regulator of Tissue and Organ Development (G3199)

Target Name: HOXA2

NCBI ID: G3199

HOXA2

HOX-A2: A Key Regulator of Tissue and Organ Development

The Homeobox protein Hox-A2 (HOXA2) is a key regulator of gene expression in many organisms, including humans. It is a member of the HOX gene family, which encodes a family of transmembrane proteins that play a central role in the development and maintenance of various tissues and organs. Hox-A2 is involved in the regulation of a wide range of physiological processes, including cell growth, differentiation, and response to environmental stimuli.

HOX-A2 is a 21-kDa protein that is expressed in many tissues and organs, including the brain, heart, and gastrointestinal tract. It is primarily localized to the cytoplasm and has been shown to play a role in regulating the expression of target genes. Hox-A2 has been shown to interact with several other proteins, including Dazl (Dazl kinase 1), which is a known co-factor of Hox-A2 and is involved in the regulation of stem cell maintenance.

HOX-A2 is a potential drug target and has been identified as a potential biomarker for several diseases, including cancer. Hox-A2 has been shown to be overexpressed in a variety of cancer types, including breast, ovarian, and prostate cancers. It is also overexpressed in diseases that are characterized by inflammation, such as rheumatoid arthritis and Crohn's disease.

HOX-A2 is involved in the regulation of a wide range of biological processes, including cell growth, differentiation, and response to environmental stimuli. It is a key regulator of the expression of target genes and has been shown to interact with several other proteins.

HOX-A2 is a 21-kDa protein that is expressed in many tissues and organs, including the brain, heart, and gastrointestinal tract. It is primarily localized to the cytoplasm and has been shown to play a role in regulating the expression of target genes.

HOX-A2 has been shown to interact with several other proteins, including Dazl, which is a known co-factor of Hox-A2 and is involved in the regulation of stem cell maintenance.

HOX-A2 is a potential drug target and has been identified as a potential biomarker for several diseases, including cancer. It is overexpressed in a variety of cancer types, including breast, ovarian, and prostate cancers. It is also overexpressed in diseases that are characterized by inflammation, such as rheumatoid arthritis and Crohn's disease.

Conclusion

HOX-A2 is a key regulator of gene expression that is involved in the regulation of a wide range of physiological processes. It is a potential drug target and has been identified as a potential biomarker for several diseases, including cancer. Further research is needed to fully understand the role of Hox-A2 in biology and to develop effective treatments for diseases associated with its dysfunction.

Protein Name: Homeobox A2

Functions: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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